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Organization and Basis of Presentation - Additional information (Details Textual) - USD ($)
6 Months Ended
Jun. 30, 2018
Dec. 31, 2017
Organization, Consolidation and Presentation of Financial Statements [Abstract]    
Accumulated deficit $ (444,329,000) $ (416,383,000)
Cash, cash equivalents, and marketable securities 55,249,000  
Working Capital $ 37,323,000  
Sufficient capital to fund its operations 1 year  
Restricted cash $ 758,000 $ 758,000
New Accounting Pronouncement or Change in Accounting Principle, Cumulative Effect of Change on Equity or Net Assets 736,000  
Capitalized Contract Cost, Amortization $ 258,000  
Instruments    
Product Warranty Liability    
Product warranty period one year  
Reagents    
Product Warranty Liability    
Product warranty period sixty day