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Organization and Basis of Presentation - Property and equipment (Details)
6 Months Ended
Jun. 30, 2018
Property and Equipment  
Finite-Lived Intangible Asset, Useful Life 10 years
Machinery and laboratory equipment | Minimum  
Property and Equipment  
Property, Plant, and Equipment, Useful Life 3 years
Machinery and laboratory equipment | Maximum  
Property and Equipment  
Property, Plant, and Equipment, Useful Life 5 years
Instruments | Minimum  
Property and Equipment  
Property, Plant, and Equipment, Useful Life 4 years
Instruments | Maximum  
Property and Equipment  
Property, Plant, and Equipment, Useful Life 5 years
Office equipment | Minimum  
Property and Equipment  
Property, Plant, and Equipment, Useful Life 3 years
Office equipment | Maximum  
Property and Equipment  
Property, Plant, and Equipment, Useful Life 7 years
Leasehold improvements  
Property and Equipment  
Property, Plant and Equipment, Estimated Useful Lives over the shorter of the remaining life of the lease or the useful economic life of the asset