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Property and Equipment, net
 6 Months Ended
Jun. 30, 2017
Property, Plant and Equipment, Net [Abstract]  
Property and Equipment, net
Property and Equipment, net
Property and equipment as of June 30, 2017 and December 31, 2016 comprised the following (in thousands):
 
June 30, 2017
 
December 31, 2016
Property and equipment — at cost:
 
 
 
Machinery and laboratory equipment
$
11,928

 
$
10,145

Instruments
11,286

 
9,869

Office equipment
1,751

 
1,714

Leasehold improvements
10,318

 
10,100

Total property and equipment — at cost
35,283

 
31,828

Less: accumulated depreciation
(15,505
)
 
(13,560
)
Property and equipment, net
$
19,778

 
$
18,268


Depreciation expense was $1,114,000 and $797,000 for the three months ended June 30, 2017 and 2016, respectively, and was $2,207,000 and $1,603,000 for the six months ended June 30, 2017 and 2016, respectively.