SCHEDULE 13D/A 0001068238-23-000046 0001645161 XXXXXXXX LIVE 6 Common Stock, $0.001 par value per share 09/02/2025 false 0001485003 14216R101 Carisma Therapeutics Inc.

3675 Market Street Suite 401 Philadelphia PA 19104

HealthCap VII, L.P. 4121 614 3500 Represented by HealthCap Investments SA 23 Avenue Villamont Lausanne V8 CH-1005 Louis E. Rambo (202) 416-6800 Proskauer Rose LLP 1001 Pennsylvania Ave. NW, Suite 600 S Washington DC 20004-2533 0001645161 N HealthCap VII, L.P. b WC N DE 0 0 0 0 0 N 0.0 PN Y HealthCap VII GP LLC b AF N DE 0 0 0 0 0 N 0.0 PN Common Stock, $0.001 par value per share Carisma Therapeutics Inc. 3675 Market Street Suite 401 Philadelphia PA 19104 This Amendment No. 6 to Schedule 13D is being filed to correct the reported number of shares beneficially owned by the Reporting Persons, the number of shares reported to be sold by the Reporting Persons in Item 5(c), and the date the Reporting Persons ceased to be the beneficial owners of more than five percent of the Common Stock, as reported in Amendment No. 5 to this Schedule 13D filed on August 29, 2025. Items 5(a)-(c) and 5(e) of the Schedule 13D are hereby amended and supplemented as follows: The information set forth in rows 11 and 13 of the cover pages to this Schedule 13D is incorporated by reference. The information set forth in rows 7 through 10 of the cover pages to this Schedule 13D is incorporated by reference. The Reporting Persons have effected the following transactions related to the Common Stock since the filing of Amendment No. 4 to the Schedule 13D on August 29, 2025: Sold 147,884 shares of Common Stock on August 22, 2025 at a price of $0.231 per share; sold 92,900 shares of Common Stock on August 25, 2025 at a price of $0.231 per share; sold 80,201 shares of Common Stock on August 26, 2025 at a price of $0.235 per share; sold 110,214 shares of Common Stock on August 27, 2025 at a price of $0.229 per share; sold 82,194 shares of Common Stock on August 28, 2025 at a price of $0.22765 per share; sold 91,852 shares of Common Stock on August 29, 2025 at a price of $0.22037 per share; and sold 2,116,678 shares of Common Stock on September 2, 2025 at a price of $0.46802 per share. On September 2, 2025, the Reporting Persons ceased to be the beneficial owners of more than five percent of the Common Stock. HealthCap VII, L.P. /s/ Dag Richter 09/02/2025 /s/ Fabrice Bernhard 09/02/2025 HealthCap VII GP LLC /s/ Dag Richter 09/02/2025 /s/ Fabrice Bernhard 09/02/2025