Liquidity, Going Concern and Management Plans - Narrative (Details) - USD ($) $ / shares in Units, $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021	Jun. 27, 2022	Jan. 01, 2022	Dec. 31, 2021
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Cash, cash equivalents, restricted cash, and restricted cash equivalents	$ 207,352		$ 207,352				$ 379,406
Short-term investments	100,000		100,000		$ 100,000		0
Working capital deficit	38,500		38,500
Accumulated deficit	(1,406,107)		(1,406,107)			$ (996,611)	$ (1,009,293)
Net loss	$ (152,746)	$ (105,865)	(409,837)	$ (270,981)
ATM Offering
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Sale of stock, consideration received on transaction			229,000
Payments of stock issuance costs			$ 4,900
Number of shares issued in transaction			31,658,931
Sale of stock, price per share (in usd per share)	$ 7.39		$ 7.39