X0306 4 2023-02-16 0 0001484612 Outset Medical, Inc. OM 0001304125 Trigg Leslie 3052 ORCHARD DRIVE SAN JOSE CA 95134 1 1 0 0 Chair and CEO Common Stock 2023-02-16 4 S 0 932 24.36 D 413112 D Common Stock 2023-02-16 4 S 0 2083 24.36 D 411029 D Common Stock 8770 I Trigg Family Trust Required number of shares sold by the reporting person to cover tax withholding obligations in connection with the vesting of 1,821 shares of Common Stock underlying RSUs granted to the reporting person on March 15, 2021. This sale was made to satisfy tax withholding obligations through a "sell to cover" transaction and does not represent a discretionary trade by the reporting person. Required number of shares sold by the reporting person to cover tax withholding obligations in connection with the vesting of 4,071 shares of Common Stock underlying RSUs granted to the reporting person on January 26, 2022. This sale was made to satisfy tax withholding obligations through a "sell to cover" transaction and does not represent a discretionary trade by the reporting person. By: John L Brottem For: Leslie Trigg 2023-02-16