X0306 4/A 2021-03-15 2021-03-17 0001484612 Outset Medical, Inc. OM 0001823381 Brottem John L. 3052 ORCHARD DRIVE SAN JOSE CA 95134 true General Counsel Stock Option (Right to Buy) 50.01 2021-03-15 4 A 0 22209 0 A 2031-03-14 Common Stock 22209 22209 D This option vests 25% on March 15, 2022, and then in 36 equal monthly installments thereafter, subject to the reporting person's continued employment through the applicable vesting date. This Form 4 amendment is being filed to correct the exercise price. /s/ John L. Brottem 2021-03-18