X0306 4 2021-03-15 0001484612 Outset Medical, Inc. OM 0001823380 Vazquez Martin 3052 ORCHARD DRIVE SAN JOSE CA 95134 true Chief Operating Officer Common Stock 2021-03-15 4 A 0 8255 0 A 9255 D Stock Option (Right to Buy) 25.89 2021-03-15 4 A 0 16416 0 A 2031-03-14 Common Stock 16416 16416 D Represents restricted stock units ("RSU") granted to the reporting person on March 15, 2021. Each RSU represents a contingent right to receive one share of common stock. These RSUs shall vest 25% on March 15, 2022, then quarterly over three years on each February 15th, May 15th, August 15th and November 15th, subject to the reporting person's continuous service through the applicable vesting date. This option vests 25% on March 15, 2022, and then in 36 equal monthly installments thereafter, subject to the reporting person's continued employment through the applicable vesting date. /s/ John Brottem, attorney-in-fact for Martin Vazquez 2021-03-17