Description of Business - Additional Information (Detail) - USD ($) $ in Thousands	3 Months Ended				6 Months Ended
	Jun. 30, 2022	Mar. 31, 2022	Jun. 30, 2021	Mar. 31, 2021	Jun. 30, 2022	Jun. 30, 2021	Dec. 31, 2021
Description Of Business [Line Items]
Proceeds from issuance of common stock upon follow-on public offering, net of issuance costs					$ 0	$ 149,085
Net loss	$ 43,839	$ 36,892	$ 30,208	$ 30,025	80,731	$ 60,233
Accumulated deficit	(706,725)				(706,725)		$ (625,994)
Cash, cash equivalents and short-term investments	262,100				262,100
Restricted cash	33,311				33,311		$ 33,311
Cash, cash equivalents, restricted cash and short-term investments	$ 295,400				$ 295,400