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Net loss per share
3 Months Ended
Mar. 31, 2017
Earnings Per Share [Abstract]  
Net loss per share
Net loss per share
Basic net loss per share is computed by dividing net loss by the weighted-average number of Common Stock actually outstanding during the period including contingent shares to be issued to Essentialis stockholders of 913,379 shares of common stock to be issued on the 1 year anniversary of the closing of the merger and 4,566,948 shares of common stock to be issued upon the achievement of a development milestone. Diluted net loss per share is computed by dividing net loss by the weighted-average number of Common Stock outstanding and dilutive potential Common Stock that would be issued upon the exercise of Common Stock warrants and options. For the three months ended March 31, 2017 and 2016 the effect of issuing the potential Common Stock is anti-dilutive due to the net losses in those periods and the number of shares used to compute basic and diluted earnings per share are the same in each of those periods.
The following potentially dilutive securities outstanding have been excluded from the computations of diluted weighted-average shares outstanding because such securities have an antidilutive impact due to losses reported (in Common Stock equivalent shares):
 
Three Months Ended March 31,
 
 
2017
 
2016
 
Series A Convertible preferred stock

 
4,505,405

 
Series B Convertible preferred stock
12,179,000

 

 
Warrants issued to 2010/2012 convertible note holders to purchase common stock
510,350

 
510,350

 
Options to purchase common stock
2,934,857

 
2,297,639

 
Warrants issued in 2009 to purchase common stock
9,259

 
9,259

 
Warrants issued to underwriter to purchase common stock
82,500

 
82,500

 
Series A Warrants to purchase common stock
2,425,605

 
2,425,605

 
Series C Warrants to purchase common stock
590,415

 
590,415

 
Series D Warrants to purchase common stock
2,930,812

 
2,810,812