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Income Taxes - Reconciliation of Income Tax Expense by Applying Statutory U.S. Federal Income Tax Rate to Income Before Income Taxes (Detail) - USD ($)
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Effective Income Tax Rate Reconciliation, Amount [Abstract]    
Tax on the loss before income tax expense computed at the federal statutory rate of 34% $ (4,094,922) $ (5,408,551)
State tax (benefit) at statutory rate, net of federal benefit (266,258) (928,107)
Foreign Rate Differential 35,343 0
Change in Valuation Allowance 4,260,571 4,199,154
Change in research and development credits (129,974) (60,991)
Stock Based Compensation - ISO 323,537 0
Change in fair value of warrants (619,067) 1,493,215
Change in state tax rate 345,172 0
Other 167,298 705,280
Provision for deferred taxes $ 21,700 $ 0
Effective income tax rate 0.00% 0.00%
Federal statutory rate percentage 34.00% 34.00%