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Net loss per share (Tables)
12 Months Ended
Dec. 31, 2015
Earnings Per Share [Abstract]  
Schedule of Potentially Dilutive Securities Outstanding Excluded from Computations of Diluted Weighted-Average Shares Outstanding
The following potentially dilutive securities outstanding have been excluded from the computations of diluted weighted-average shares outstanding because such securities have an antidilutive impact due to losses reported (in Common Stock equivalent shares):
 
As of December 31,
 
2015
 
2014
Convertible preferred stock
2,462,162

 

Warrants issued to 2010/2012 convertible note holders to purchase common stock
480,147

 
523,867

Options to purchase common stock
1,858,839

 
1,072,011

Warrants issued in 2009 to purchase common stock
9,259

 
9,259

Warrants issued to underwriter to purchase common stock
82,500

 
82,500

Series A warrants to purchase common stock
2,425,605

 
2,449,605

Series B warrants to purchase common stock
116,580

 
2,449,605

Series C warrants to purchase common stock
590,415

 

Series D warrants to purchase common stock
1,280,324