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Stockholders' Equity - Summary of Stock Option Transactions (Detail) - Stock Options [Member] - $ / shares
3 Months Ended 12 Months Ended
Mar. 31, 2019
Mar. 31, 2018
Dec. 31, 2018
Shares Available for Grant      
Options Available, Beginning balance 1,150,961    
Options Available, Additional shares authorized 223,742    
Options Available, Granted (464,000)    
Options Available, Exercised 0    
Options Available, Canceled/Forfeited 15,046    
Options Available, Ending balance 925,749   1,150,961
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding [Roll Forward]      
Beginning balance 1,667,153    
Options granted 464,000 616,500  
Options exercised 0    
Options canceled/forfeited (15,046)    
Ending balance 2,116,107   1,667,153
Options vested at end of period (shares) 901,140    
Options vested and expected to vest at end of period (shares) 2,116,107    
Weighted-Average Exercise Price per Share      
Beginning balance (in dollars per share) $ 6.03    
Options granted (in dollars per share) 1.67    
Options exercised (in dollars per share) 0    
Options canceled/forfeited (in dollars per share) 8.83    
Ending balance (in dollars per share) 5.05   $ 6.03
Options vested at end of period (in dollars per share) 9.14    
Options vested and expected to vest at end of period (in dollars per share) $ 5.05    
Weighted Average Remaining Contractual Term      
Options outstanding at end of period 8 years 5 months 4 days   8 years 3 months 7 days
Options vested at end of period 7 years 6 months 7 days    
Options vested and expected to vest at end of period 8 years 5 months 4 days