Document and Entity Information	12 Months Ended
	Dec. 31, 2018
Document And Entity Information [Abstract]
Document Type	S-1
Amendment Flag	false
Document Period End Date	Dec. 31, 2018
Entity Registrant Name	SOLENO THERAPEUTICS INC
Entity Central Index Key	0001484565
Entity Filer Category	Non-accelerated Filer
Entity Small Business	true
Entity Emerging Growth Company	true
Entity Ex Transition Period	false