X0508 4 2023-12-13 0 0001484565 SOLENO THERAPEUTICS INC SLNO 0001766042 Hirano Patricia C 203 REDWOOD SHORES PKWY, STE 500 REDWOOD CITY CA 94065 0 1 0 0 See Remarks 0 Common Stock 2023-12-13 4 S 0 4885 38.7948 D 21333 D Common Stock 2023-12-14 4 S 0 1359 36.4853 D 19974 D This transaction was executed in multiple trades at prices ranging from $38.7815 to $38.885. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price. Certain of these securities are restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of Common Stock, subject to the applicable vesting schedule and conditions of each RSU. This transaction was executed in multiple trades at prices ranging from $36.48 to $36.50. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price. /s/ Anish Bhatnagar, Attorney-in-Fact 2023-12-15