Long-term Debt - Additional Information (Details) $ in Thousands	3 Months Ended
	Mar. 31, 2025 USD ($) Installment	Dec. 17, 2024 USD ($)
Debt Instrument [Line Items]
Number of installments | Installment	11
Interest expense	$ 1,361
Principal amount of term loans	$ 50,000
Loan And Security Agreement [Member] | Oxford [Member]
Debt Instrument [Line Items]
Debt instrument, face amount		$ 200,000
Debt instrument interest period	48 months
Debt instrument term	60 months
Debt instrument maturity extension period	12 months
Debt Instrument interest rate stated percentage	5.50%
Debt instrument payment terms	The loan carries an interest-only period of 48 months and a total term of 60 months; provided that if specific milestones are achieved prior to September 30, 2026, the interest-only period and maturity date will be extended by 12 months. The term loans accrue interest, payable monthly, at a floating rate equal to, subject to certain conditions, (a) 1-month term SOFR plus (b) 5.50%. The principal portion of the loan is due in eleven equal monthly installments beginning February 1, 2029, through December 1, 2029.
Debt instrument date of first required payment	Feb. 01, 2029
Debt instrument date of final required payment	Dec. 01, 2029
Debt instrument frequency of periodic payment	monthly
Debt instrument maturity date description	However, if a specified milestone is achieved on or after December 17, 2025, then the term loan will begin to amortize in equal monthly installments beginning on February 1, 2030, and the maturity date will be extended to December 1, 2030
Final principal fee payment percentage	5.00%
Debt instrument final interest payment	$ 2,500
Amount borrowed	50,000
Long-term accrued interest payable	145
Loan issuance costs	174
Principal amount of term loans	$ 50,000
Percentage of increase in applicable rate of interest under termination of the lenders' commitments	5.00%
Debt instrument fee	6.50%
Loan And Security Agreement [Member] | Oxford [Member] | Minimum [Member]
Debt Instrument [Line Items]
Principal amount of term loans	$ 50,000
Loan And Security Agreement [Member] | FDA Approval OF VYKATXR Tranche one [Member] | Oxford [Member]
Debt Instrument [Line Items]
Debt instrument additional borrowing amount	$ 50,000
Debt instrument date of final borrowings	Sep. 30, 2025
Loan And Security Agreement [Member] | FDA Approval OF VYKATXR Tranche Two [Member] | Oxford [Member]
Debt Instrument [Line Items]
Debt instrument additional borrowing amount	$ 25,000
Debt instrument date of first borrowings	Oct. 01, 2025
Debt instrument date of final borrowings	Sep. 30, 2026
Loan And Security Agreement [Member] | Contingent upon certain commercial milestones [Member] | Oxford [Member]
Debt Instrument [Line Items]
Debt instrument additional borrowing amount	$ 25,000
Loan And Security Agreement [Member] | Mutual Consent of Soleno and Oxford [Member] | Oxford [Member]
Debt Instrument [Line Items]
Debt instrument additional borrowing amount	$ 50,000
Loan And Security Agreement [Member] | Milestone Achieved on or After December 17, 2025 [Member] | Oxford [Member]
Debt Instrument [Line Items]
Debt instrument date of first required payment	Feb. 01, 2030
Debt instrument date of final required payment	Dec. 01, 2030
Loan And Security Agreement [Member] | Milestone Achieved on or After December 17, 2025 [Member] | Oxford [Member] | 5% Interest on Total Loan Amount on Final Principal Payment [Member]
Debt Instrument [Line Items]
Debt instrument maturity start date	Feb. 01, 2030
Debt instrument maturity end date	Dec. 01, 2030