Fair Value of Financial Instruments - Summary of Financial Instruments Measured at Fair Value on Recurring Basis (Detail) - USD ($) $ in Thousands	Mar. 31, 2025	Dec. 31, 2024
Liabilities
Essentialis purchase price contingency liability	$ 17,758	$ 14,791
Fair Value, Measurements, Recurring [Member]
Assets
Total cash equivalents	48,298	59,885
Total marketable securities	208,619	230,720
Total assets	256,917	290,605
Liabilities
Essentialis purchase price contingency liability	17,758	14,791
Total liabilities	17,758	14,791
Fair Value, Measurements, Recurring [Member] \| Money Market Funds [Member]
Assets
Total cash equivalents	48,298	59,885
Fair Value, Measurements, Recurring [Member] \| US Treasury Securities [Member]
Assets
Total marketable securities	133,311	198,065
Fair Value, Measurements, Recurring [Member] \| Corporate Debt Securities and Commercial Paper [Member]
Assets
Total marketable securities	75,308	32,655
Level 1 [Member] \| Fair Value, Measurements, Recurring [Member]
Assets
Total cash equivalents	48,298	59,885
Total assets	48,298	59,885
Level 1 [Member] \| Fair Value, Measurements, Recurring [Member] \| Money Market Funds [Member]
Assets
Total cash equivalents	48,298	59,885
Level 2 [Member] \| Fair Value, Measurements, Recurring [Member]
Assets
Total marketable securities	208,619	230,720
Total assets	208,619	230,720
Level 2 [Member] \| Fair Value, Measurements, Recurring [Member] \| US Treasury Securities [Member]
Assets
Total marketable securities	133,311	198,065
Level 2 [Member] \| Fair Value, Measurements, Recurring [Member] \| Corporate Debt Securities and Commercial Paper [Member]
Assets
Total marketable securities	75,308	32,655
Level 3 [Member] \| Fair Value, Measurements, Recurring [Member]
Liabilities
Essentialis purchase price contingency liability	17,758	14,791
Total liabilities	$ 17,758	$ 14,791

Amount of liability recognized from contingent consideration in asset acquisition, classified as noncurrent.

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Fair value portion of asset recognized for present right to economic benefit.

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Amount of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale), classified as current.

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Fair value portion of currency on hand as well as demand deposits with banks or financial institutions. Includes other kinds of accounts that have the general characteristics of demand deposits. Also includes short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates.

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Fair value of financial and nonfinancial obligations.

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