Stockholders' Equity - Additional Information (Detail) - USD ($)						1 Months Ended			3 Months Ended		6 Months Ended		12 Months Ended
	Jul. 17, 2024	May 09, 2024	Oct. 02, 2023	Sep. 26, 2023	Dec. 16, 2022	Oct. 31, 2023	Mar. 31, 2022	Jul. 31, 2021	Jun. 30, 2024	Jun. 30, 2023	Jun. 30, 2024	Jun. 30, 2023	Dec. 31, 2023	Dec. 31, 2022	Jun. 06, 2024	Jan. 24, 2024	Jan. 17, 2024
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Proceeds from the sale of common stock, net of issuance costs											$ 148,955,000	$ 7,099,000
Proceeds from issuance or sale of equity			$ 129,000,000
Public offering price per pre-funded warrant			$ 19.99
Offering costs						$ 8,200,000
Number of Common Warrant Shares									9,969,795		9,969,795		13,071,883
Expected dividend yield									0.00%	0.00%	0.00%	0.00%
Weighted average grant date fair value per option granted (in dollars per share)											$ 36.34	$ 3.79
Number of shares available for issuance under the plan on the first day of each year									38,386,779		38,386,779		31,678,159
Convertible preferred stock, shares authorized									10,000,000		10,000,000		10,000,000
Tranche A [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Sale and issuance of warrants to purchase common stock				$ 15,000,000
Number of Common Warrant Shares					8,598,870
Warrants and rights immediately exercisable term					30 days
Weighted Average Exercise Price per Share					$ 1.75
Exercisable warrants maximum aggregate exercise price					$ 15,000,000
Tranche B [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Contingent receipt upon exerise of warrants and future performance of company											$ 14,400,000
Number of Common Warrant Shares					14,000,000
Proceeds from warrant exercise											$ 20,600,000
Warrants expire term prior to anniversary date of issuance					3 years 6 months
Warrants and rights exercisable term from following receipt of U.S. Food and drug administration approval					30 days
Weighted Average Exercise Price per Share					$ 2.50
Exercisable warrants maximum aggregate exercise price					$ 35,000,000
Minimum [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Ownership interest of voting rights of all classes of stock (percent)									10.00%		10.00%
2020 Inducement Equity Incentive Plan [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Number of shares available for grant									149,168		149,168					500,000
Stock Options [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Income tax benefits recognized from stock-based compensation									$ 0	$ 0	$ 0	$ 0
Number of options granted									343,700	1,346,454	1,080,380	1,586,454
Future stock-based compensation for unvested employee options granted and outstanding									$ 41,600,000		$ 41,600,000
Future stock-based compensation, requisite service period											2 years 8 months 12 days
Stock Options [Member] | 2014 Equity Incentive Plan [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Number of shares available for grant									2,359,544		2,359,544				2,000,000		1,000,000
Stock Options [Member] | 2014 Equity Incentive Plan [Member] | Minimum [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Percentage of fair market value											110.00%
Stock Options [Member] | 2014 Equity Incentive Plan [Member] | Maximum [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Contractual term of option											10 years
ISOs [Member] | 2014 Equity Incentive Plan [Member] | Maximum [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Contractual term of option											5 years
Restricted Stock Units [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Restricted stock units vested											74,250
Unrecognized stock based compensation expense									$ 8,300,000		$ 8,300,000
Stock units granted									32,500	414,710	391,530	414,710
Fair value of restricted stock units vested											$ 6,800,000	$ 23,000,000
Weighted average grant-date fair value of all restricted stock units granted											$ 37.58	$ 5.25
Weighted average remaining vesting period											6 months
Restricted Stock Units [Member] | 2014 Equity Incentive Plan [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Restricted Stock units											$ 37.67
Restricted stock units vested											161,034
Stock units granted											401,530
Weighted average grant-date fair value of all restricted stock units granted											$ 37.58
Performance-Based Restricted Stock Units [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Shares granted to date											10,000
Warrants to Purchase Stock [Member] | 2010 and 2012 Convertible Promissory Notes [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Number of Common Warrant Shares									6,804		6,804
Weighted Average Exercise Price per Share									$ 365.25		$ 365.25
Warrants term											10 years
Expiration period											2024-11
Underwriter [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Number of Common Warrant Shares									1,100		1,100
Weighted Average Exercise Price per Share									$ 535.5		$ 535.5
Warrants term											10 years
Expiration period											2024-11
March 2022 Common Warrants [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Number of Common Warrant Shares									1,483,743		1,483,743		1,929,066
Weighted Average Exercise Price per Share									$ 4.50		$ 4.50		$ 4.50
Expiration period											2027-03
Controlled Equity Offering Sales Agreement [Member] | Cantor [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Issuance of common stock (shares)													1,877,170
Proceeds from the sale of common stock, net of issuance costs								$ 7,400,000
Common stock, maximum aggregate purchase price								$ 25,000,000
Securities Purchase Agreement [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Sale and issuance of warrants to purchase common stock											$ 10,000,000
Shares issued from sale of common stock			1,825,000
Shares issued from sale of pre-funded warrants			1,175,000
Proceeds from sale of common stock and pre-funded warrants			$ 60,000,000
Number of common stock purchased upon issuance of warrants					22,598,870
Proceeds from warrant exercise											35,600,000
Weighted Average Exercise Price per Share					$ 0.4425
Exercisable warrants maximum aggregate exercise price									$ 14,400,000		14,400,000
Underwritten Public Offering [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Issuance of common stock (shares)		3,450,000	3,450,000				2,666,667
Price per unit		$ 46.00	$ 20.00				$ 3.75
Underwriter discount and other offering expenses		$ 9,700,000
Number of common stock purchased upon issuance of warrants							1,333,333
Public offering price per pre-funded warrant							$ 3.60
Per share exercise price for pre-funded warrant							$ 0.15
Measurement term							5 years
Proceeds from offering after deducting underwriting discount and other estimated offering expenses		$ 158,700,000	$ 69,000,000				$ 13,800,000
Proceeds from warrant exercise											$ 0
Weighted Average Exercise Price per Share							$ 4.50
Warrants exercised											1,333,333
Underwritten Public Offering [Member] | March 2022 Common Warrants [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Proceeds from warrant exercise											$ 11,300,000
Warrants exercised											2,516,257
Underwritten Public Offering [Member] | Securities Purchase Agreement [Member] | Maximum [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Proceeds from the sale of common stock, net of issuance costs														$ 60,000,000
Employee Stock Purchase Plan [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Number of shares available for grant									1,864		1,864
Percentage of outstanding stock maximum											1.00%
Number of shares available for issuance under the plan on the first day of each year									3,729		3,729
Number of shares purchases by employees											0
Public Offering [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Price per unit			$ 20.00
Board of Directors [Member] | Performance-Based Restricted Stock Units [Member] | 2014 Equity Incentive Plan [Member] | Subsequent Event [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Unrecognized stock based compensation expense	$ 77,500,000
Stock units granted	1,593,000