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Net Loss per Share - Schedule of Potentially Dilutive Securities Outstanding Excluded from Computations of Diluted Weighted-Average Shares Outstanding (Detail) - shares
3 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Antidilutive securities excluded from computations of diluted weighted-average shares outstanding 4,978,004 4,577,823
Warrants Issued to 2010/2012 Convertible Note Holders to Purchase Common Stock [Member]    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Antidilutive securities excluded from computations of diluted weighted-average shares outstanding 6,804 6,804
Options to Purchase Common Stock [Member]    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Antidilutive securities excluded from computations of diluted weighted-average shares outstanding 926,325 516,445
Outstanding Restricted Stock Units [Member]    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Antidilutive securities excluded from computations of diluted weighted-average shares outstanding 9,534 19,233
Warrants Issued to Underwriter to Purchase Common Stock [Member]    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Antidilutive securities excluded from computations of diluted weighted-average shares outstanding 1,100 1,100
2018 PIPE Warrants [Member]    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Antidilutive securities excluded from computations of diluted weighted-average shares outstanding 34,241 34,241
2022 Common Warrants [Member]    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Antidilutive securities excluded from computations of diluted weighted-average shares outstanding 4,000,000 4,000,000