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Stockholders' Equity - Summary of Stock Option Transactions (Detail) - Stock Options [Member] - $ / shares
3 Months Ended 12 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Dec. 31, 2022
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding [Roll Forward]      
Options granted 240,000 108,517  
2014 Plan and Inducement Plan [Member]      
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding [Roll Forward]      
Beginning balance 686,574    
Options granted 240,000    
Options canceled/forfeited (249)    
Ending balance 926,325   686,574
Options exercisable at end of period (shares) 428,551    
Options vested and expected to vest at end of period (shares) 903,367    
Weighted-Average Exercise Price per Share      
Beginning balance (in dollars per share) $ 28.83    
Options granted (in dollars per share) 2.37    
Options canceled/forfeited (in dollars per share) 2.80    
Ending balance (in dollars per share) 21.98   $ 28.83
Options exercisable at end of period (in dollars per share) 34.46    
Options vested and expected to vest at end of period (in dollars per share) $ 20.61    
Weighted Average Remaining Contractual Term      
Options outstanding at end of period 8 years 2 months 15 days   7 years 11 months 4 days
Options exercisable at end of period 7 years 3 months 18 days    
Options vested and expected to vest at end of period 8 years 3 months 10 days