Income Taxes - Additional Information (Detail) - USD ($)	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Income Tax Contingency [Line Items]
Increase (decrease) in valuation allowance	$ 5,700,000
Unrecognized assets and liabilities related to uncertain tax positions	1,900,000
Unrecognized Tax Benefits that Would Impact Effective Tax Rate	0	$ 0
Unrecognized tax benefit offset by change in valuation allowance	1,900,000
Internal Revenue Service (IRS) [Member]
Income Tax Contingency [Line Items]
Operating loss carryforwards	$ 500,000
Minimum [Member]
Income Tax Contingency [Line Items]
Research and development costs, amortization period	5 years
Maximum [Member]
Income Tax Contingency [Line Items]
Research and development costs, amortization period	15 years
U.S. Federal Jurisdiction [Member]
Income Tax Contingency [Line Items]
Operating loss carryforwards	$ 195,000,000.0
Operating loss carryforwards, carried forward indefinitely	90,100,000
U.S. Federal Jurisdiction [Member] | Research Tax Credit Carryforward [Member]
Income Tax Contingency [Line Items]
Tax credit carryforwards	3,900,000
State Tax Jurisdiction [Member]
Income Tax Contingency [Line Items]
Operating loss carryforwards	110,400,000
State Tax Jurisdiction [Member] | Research Tax Credit Carryforward [Member]
Income Tax Contingency [Line Items]
Tax credit carryforwards	2,500,000
Foreign Tax Authority [Member] | Her Majesty's Revenue and Customs (HMRC) [Member]
Income Tax Contingency [Line Items]
Operating loss carryforwards	$ 2,500,000