Income Taxes - Significant Components of Company's Deferred Tax Assets and Liabilities (Detail) - USD ($) $ in Thousands	Dec. 31, 2022	Dec. 31, 2021
Non-current deferred tax assets:
Federal and state net operating loss carryforwards	$ 49,024	$ 48,542
Research and other credits	4,146	3,312
Capitalized research and development	2,828
Reserves and accruals	547	573
Fixed assets	44	59
Capital loss carryover	555	1,115
Stock based compensation	2,682	1,133
Lease liability	42	133
Other deferred tax assets	72	102
Gross non-current deferred tax assets	59,940	54,969
Intangible assets	(2,888)	(3,536)
Right-of-use assets	(35)	(118)
Total non-current deferred tax liabilities	(2,923)	(3,654)
Total deferred tax assets	57,017	51,315
Valuation allowance	$ (57,017)	$ (51,315)