0001214659-21-001839.txt : 20210216 0001214659-21-001839.hdr.sgml : 20210216 20210216130325 ACCESSION NUMBER: 0001214659-21-001839 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20201231 FILED AS OF DATE: 20210216 DATE AS OF CHANGE: 20210216 EFFECTIVENESS DATE: 20210216 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Sio Capital Management, LLC CENTRAL INDEX KEY: 0001482416 IRS NUMBER: 204586565 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-13691 FILM NUMBER: 21635316 BUSINESS ADDRESS: STREET 1: 600 THIRD AVENUE STREET 2: 2ND FLOOR CITY: NEW YORK STATE: NY ZIP: 10016 BUSINESS PHONE: 212-601-9786 MAIL ADDRESS: STREET 1: 600 THIRD AVENUE STREET 2: 2ND FLOOR CITY: NEW YORK STATE: NY ZIP: 10016 13F-HR 1 primary_doc.xml 13F-HR LIVE false false false 0001482416 XXXXXXXX 12-31-2020 12-31-2020 false Sio Capital Management, LLC

600 Third Avenue 2nd Floor New York NY 10016

13F HOLDINGS REPORT 028-13691 N Judah Drillick 212-601-9787 /s/Judah Drillick New York NY 02-16-2021 0 89 488530 INFORMATION TABLE 2 infotable.xml AEGLEA BIOTHERAPEUTICS INC COM 00773J103 1504 191104 SH SOLE 191104 0 0 AGIOS PHARMACEUTICALS INC COM 00847X104 1517 35000 SH SOLE 35000 0 0 ALBIREO PHARMA INC COM 01345P106 13286 354210 SH SOLE 354210 0 0 ALPHA HEALTHCARE ACQUISITION CORP UNIT 09/21/2027 020751202 1057 100000 SH SOLE 100000 0 0 AMERISOURCEBERGEN CORP COM 03073E105 12492 127781 SH SOLE 127781 0 0 AMGEN INC COM 031162100 9197 40000 SH SOLE 40000 0 0 AMN HEALTHCARE SERVICES INC COM 001744101 8913 130598 SH SOLE 130598 0 0 ANIKA THERAPEUTICS INC COM 035255108 2959 65382 SH SOLE 65382 0 0 ARDELYX INC COM 039697107 4460 689321 SH SOLE 689321 0 0 ARENA PHARMACEUTICALS INC COM NEW 040047607 4436 57738 SH SOLE 57738 0 0 ASGN INC COM 00191U102 5269 63077 SH SOLE 63077 0 0 ASLAN PHARMACEUTICALS LTD ADS 04522R101 2549 1392654 SH SOLE 1392654 0 0 ASTRAZENECA PLC SPONSORED ADR 046353108 13147 263000 SH SOLE 263000 0 0 ATRECA INC CL A COM 04965G109 2075 128455 SH SOLE 128455 0 0 AYALA PHARMACEUTICALS INC COM 05465V108 1723 156655 SH SOLE 156655 0 0 BECTON DICKINSON AND CO COM 075887109 6835 27314 SH SOLE 27314 0 0 BIOMARIN PHARMACEUTICAL INC COM 09061G101 8843 100844 SH SOLE 100844 0 0 CARDIFF ONCOLOGY INC COM 14147L108 2695 149833 SH SOLE 149833 0 0 CARDINAL HEALTH INC COM 14149Y108 8313 155217 SH SOLE 155217 0 0 CASI PHARMACEUTICALS INC COM 14757U109 600 203432 SH SOLE 203432 0 0 CATALYST BIOSCIENCES INC COM NEW 14888D208 1191 188714 SH SOLE 188714 0 0 CELLECTAR BIOSCIENCES INC COM PAR 15117F500 4849 2331123 SH SOLE 2331123 0 0 CEL-SCI CORP COM PAR NEW 150837607 24726 2120600 SH Put SOLE 2120600 0 0 CERECOR INC COM 15671L109 2449 927746 SH SOLE 927746 0 0 CHARDAN HEALTHCARE ACQUISITION 2 CORP UNIT 15957T206 4236 400000 SH SOLE 400000 0 0 CIGNA CORP COM 125523100 12962 62265 SH SOLE 62265 0 0 COHERUS BIOSCIENCES INC COM 19249H103 15017 864056 SH SOLE 864056 0 0 CONSTELLATION PHARMACEUTICALS INC COM 210373106 2664 92500 SH SOLE 92500 0 0 CROSS COUNTRY HEALTHCARE INC COM 227483104 4303 485164 SH SOLE 485164 0 0 CURIS INC COM NEW 231269200 38955 4756438 SH SOLE 4756438 0 0 CYMABAY THERAPEUTICS INC COM 23257D103 3371 587339 SH SOLE 587339 0 0 DEERFIELD HEALTHCARE TECHNOLOGY ACQUISITIONS CORP UNIT 07/16/2025 244413209 750 50000 SH SOLE 50000 0 0 ESSA PHARMA INC COM NEW 29668H708 5166 433023 SH SOLE 433023 0 0 EUCRATES BIOMEDICAL ACQUISITION CORP. UNIT 10/23/2027 G3141W114 3198 300000 SH SOLE 300000 0 0 FULCRUM THERAPEUTICS INC COM 359616109 1713 146272 SH SOLE 146272 0 0 FUSION PHARMACEUTICALS INC COM 36118A100 2029 172693 SH SOLE 172693 0 0 GW PHARMACEUTICALS PLC ADS 36197T103 3901 33801 SH SOLE 33801 0 0 HARROW HEALTH INC COM 415858109 1438 209623 SH SOLE 209623 0 0 HCA HEALTHCARE INC COM 40412C101 13279 80745 SH SOLE 80745 0 0 HEALTH SCIENCES ACQUISITIONS CORPORATION 2 ORD SHS G4411D109 3203 250000 SH SOLE 250000 0 0 HERBALIFE NUTRITION LTD COM SHS G4412G101 3732 77660 SH SOLE 77660 0 0 HILL-ROM HOLDINGS INC COM 431475102 12070 123198 SH SOLE 123198 0 0 HORIZON THERAPEUTICS PLC SHS G46188101 7235 98901 SH SOLE 98901 0 0 IDEAYA BIOSCIENCES INC COM 45166A102 676 48298 SH SOLE 48298 0 0 I-MAB SPONSORED ADS 44975P103 707 15000 SH SOLE 15000 0 0 INTEGER HOLDINGS CORP COM 45826H109 3791 46699 SH SOLE 46699 0 0 IONIS PHARMACEUTICALS INC COM 462222100 4581 81026 SH SOLE 81026 0 0 IOVANCE BIOTHERAPEUTICS INC COM 462260100 2506 54000 SH SOLE 54000 0 0 KURA ONCOLOGY INC COM 50127T109 4320 132283 SH SOLE 132283 0 0 LARIMAR THERAPEUTICS INC COM 517125100 4039 188661 SH SOLE 188661 0 0 MCKESSON CORP COM 58155Q103 8255 47462 SH SOLE 47462 0 0 MEDIFAST INC COM 58470H101 3573 18200 SH Put SOLE 18200 0 0 MEI PHARMA INC COM NEW 55279B202 1125 426047 SH SOLE 426047 0 0 MERSANA THERAPEUTICS INC COM 59045L106 4922 184959 SH SOLE 184959 0 0 MESOBLAST LTD SPONS ADR 590717104 3543 417300 SH Put SOLE 417300 0 0 MIRUM PHARMACEUTICALS INC COM 604749101 8638 494743 SH SOLE 494743 0 0 MOLINA HEALTHCARE INC COM 60855R100 3991 18763 SH SOLE 18763 0 0 NATUS MEDICAL INC COM 639050103 3744 186833 SH SOLE 186833 0 0 NEOLEUKIN THERAPEUTICS INC COM 64049K104 540 38312 SH SOLE 38312 0 0 NEUBASE THERAPEUTICS INC COM 64132K102 2053 293699 SH SOLE 293699 0 0 ODONATE THERAPEUTICS INC COM 676079106 1450 75500 SH SOLE 75500 0 0 ONCTERNAL THERAPEUTICS INC COM 68236P107 1584 323333 SH SOLE 323333 0 0 ONTRAK INC COM 683373104 2361 38218 SH SOLE 38218 0 0 ORTHOFIX MEDICAL INC COM 68752M108 5954 138525 SH SOLE 138525 0 0 PRECISION BIOSCIENCES INC COM 74019P108 2649 317644 SH SOLE 317644 0 0 RADIUS HEALTH INC COM NEW 750469207 5236 293157 SH SOLE 293157 0 0 RAPT THERAPEUTICS INC COM 75382E109 282 14298 SH SOLE 14298 0 0 SALARIUS PHARMACEUTICALS INC COM NEW 79400X107 1508 1657242 SH SOLE 1657242 0 0 SANOFI SA SPONSORED ADR 80105N105 10700 220201 SH SOLE 220201 0 0 SIERRA ONCOLOGY INC COM NEW 82640U404 1065 66455 SH SOLE 66455 0 0 SIO GENE THERAPIES INC COM 829399104 2465 886665 SH SOLE 886665 0 0 SOLITON INC COM 834251100 6623 862405 SH SOLE 862405 0 0 SPDR GOLD SHARES GOLD SHS 78463V107 18284 102509 SH SOLE 102509 0 0 SPRUCE BIOSCIENCES INC COM 85209E109 15477 636653 SH SOLE 636653 0 0 SYNDAX PHARMACEUTICALS INC COM 87164F105 3784 170142 SH SOLE 170142 0 0 SYNEOS HEALTH INC CL A 87166B102 4428 65000 SH SOLE 65000 0 0 TEVA PHARMACEUTICAL INDUSTRIES LTD SPONSORED ADS 881624209 6662 690386 SH SOLE 690386 0 0 TRILLIUM THERAPEUTICS INC COM NEW 89620X506 228 15500 SH SOLE 15500 0 0 UNITED THERAPEUTICS CORP COM 91307C102 5879 38734 SH SOLE 38734 0 0 UNIVERSAL HEALTH SERVICES INC CL B 913903100 11116 80843 SH SOLE 80843 0 0 VAPOTHERM INC COM 922107107 2087 77707 SH SOLE 77707 0 0 VAREX IMAGING CORP COM 92214X106 4449 266740 SH SOLE 266740 0 0 VERTEX PHARMACEUTICALS INC COM 92532F100 6192 26200 SH SOLE 26200 0 0 VIEWRAY INC COM 92672L107 2961 775000 SH SOLE 775000 0 0 VIKING THERAPEUTICS INC COM 92686J106 3433 609780 SH SOLE 609780 0 0 VINCERX PHARMA INC COM 92731L106 3134 149892 SH SOLE 149892 0 0 VINCERX PHARMA INC *W EXP 12/24/2025 92731L114 693 210000 SH SOLE 210000 0 0 WALGREENS BOOTS ALLIANCE INC COM 931427108 12310 308686 SH SOLE 308686 0 0 ZOSANO PHARMA CORP COM NEW 98979H202 225 427542 SH SOLE 427542 0 0