The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| ACTINIUM PHARMACEUTICALS INC | COM | 00507W107 | 393 | 1,076,200 | SH | DFND | 0 | 1,076,200 | 0 | ||
| AETNA INC | COM | 00817Y108 | 5,346 | 31,635 | SH | DFND | 0 | 31,635 | 0 | ||
| ANTHEM INC | COM | 036752103 | 11,509 | 52,387 | SH | DFND | 0 | 52,387 | 0 | ||
| AXSOME THERAPEUTICS INC | COM | 05464T104 | 474 | 193,290 | SH | DFND | 0 | 193,290 | 0 | ||
| BIOGEN INC | COM | 09062X103 | 8,735 | 31,900 | SH | DFND | 0 | 31,900 | 0 | ||
| BOSTON SCIENTIFIC CORP | COM | 101137107 | 6,160 | 225,463 | SH | DFND | 0 | 225,463 | 0 | ||
| CATALYST BIOSCIENCES INC | COM NEW | 14888D208 | 29,670 | 1,149,989 | SH | DFND | 0 | 1,149,989 | 0 | ||
| CELGENE CORP | COM | 151020104 | 2,782 | 31,180 | SH | DFND | 0 | 31,180 | 0 | ||
| COMPUTER PROGRAMS AND SYSTEMS INC | COM | 205306103 | 3,325 | 113,860 | SH | DFND | 0 | 113,860 | 0 | ||
| CONFORMIS INC | COM | 20717E101 | 3,191 | 2,200,681 | SH | DFND | 0 | 2,200,681 | 0 | ||
| CURIS INC | COM | 231269101 | 545 | 834,551 | SH | DFND | 0 | 834,551 | 0 | ||
| DERMIRA INC | COM | 24983L104 | 1,520 | 190,300 | SH | DFND | 0 | 190,300 | 0 | ||
| ELI LILLY AND CO | COM | 532457108 | 6,372 | 82,363 | SH | DFND | 0 | 82,363 | 0 | ||
| EPIZYME INC | COM | 29428V104 | 1,293 | 72,826 | SH | DFND | 0 | 72,826 | 0 | ||
| HCA HEALTHCARE INC | COM | 40412C101 | 5,076 | 52,330 | SH | DFND | 0 | 52,330 | 0 | ||
| HERON THERAPEUTICS INC | PUT | 427746102 | 814 | 29,500 | SH | Put | DFND | 0 | 29,500 | 0 | |
| HILL-ROM HOLDINGS INC | COM | 431475102 | 1,866 | 21,449 | SH | DFND | 0 | 21,449 | 0 | ||
| ICON PLC | SHS | G4705A100 | 4,277 | 36,200 | SH | DFND | 0 | 36,200 | 0 | ||
| IMMUNOGEN INC | PUT | 45253H101 | 2,891 | 274,800 | SH | Put | DFND | 0 | 274,800 | 0 | |
| JOHNSON & JOHNSON | PUT | 478160104 | 2,563 | 20,000 | SH | Put | DFND | 0 | 20,000 | 0 | |
| KONINKLIJKE PHILIPS NV | NY REG SH NEW | 500472303 | 2,940 | 76,742 | SH | DFND | 0 | 76,742 | 0 | ||
| KURA ONCOLOGY INC | COM | 50127T109 | 12,326 | 657,411 | SH | DFND | 0 | 657,411 | 0 | ||
| MEI PHARMA INC | COM NEW | 55279B202 | 1,935 | 934,563 | SH | DFND | 0 | 934,563 | 0 | ||
| MERCK & CO INC | COM | 58933Y105 | 6,256 | 114,856 | SH | DFND | 0 | 114,856 | 0 | ||
| MYLAN NV | SHS EURO | N59465109 | 2,841 | 69,000 | SH | DFND | 0 | 69,000 | 0 | ||
| OMNICELL INC | COM | 68213N109 | 3,048 | 70,226 | SH | DFND | 0 | 70,226 | 0 | ||
| OWENS & MINOR INC | COM | 690732102 | 4,255 | 273,640 | SH | DFND | 0 | 273,640 | 0 | ||
| SANOFI SA | SPONSORED ADR | 80105N105 | 16,378 | 408,621 | SH | DFND | 0 | 408,621 | 0 | ||
| UNITEDHEALTH GROUP INC | COM | 91324P102 | 6,506 | 30,400 | SH | DFND | 0 | 30,400 | 0 | ||
| VIKING THERAPEUTICS INC | COM | 92686J106 | 5,580 | 1,276,845 | SH | DFND | 0 | 1,276,845 | 0 | ||
| WELLCARE HEALTH PLANS INC | COM | 94946T106 | 5,548 | 28,653 | SH | DFND | 0 | 28,653 | 0 | ||