0001214659-17-006698.txt : 20171114 0001214659-17-006698.hdr.sgml : 20171114 20171114160049 ACCESSION NUMBER: 0001214659-17-006698 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20170930 FILED AS OF DATE: 20171114 DATE AS OF CHANGE: 20171114 EFFECTIVENESS DATE: 20171114 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Sio Capital Management, LLC CENTRAL INDEX KEY: 0001482416 IRS NUMBER: 204586565 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-13691 FILM NUMBER: 171201321 BUSINESS ADDRESS: STREET 1: 535 FIFTH AVENUE STREET 2: SUITE 910 CITY: NEW YORK STATE: NY ZIP: 10017 BUSINESS PHONE: 212-601-9786 MAIL ADDRESS: STREET 1: 535 FIFTH AVENUE STREET 2: SUITE 910 CITY: NEW YORK STATE: NY ZIP: 10017 13F-HR 1 primary_doc.xml 13F-HR LIVE false false false 0001482416 XXXXXXXX 09-30-2017 09-30-2017 false Sio Capital Management, LLC

535 Fifth Avenue Suite 910 New York NY 10017

13F HOLDINGS REPORT 028-13691 N Albert Vigneau 212-601-9795 /s/Albert Vigneau New York NY 11-14-2017 0 54 192727 INFORMATION TABLE 2 infotable.xml ACADIA HEALTHCARE COMPANY INC PUT 00404A109 659 13800 SH Put DFND 0 13800 0 ACTINIUM PHARMACEUTICALS INC COM 00507W107 915 1590267 SH DFND 0 1590267 0 ADAMIS PHARMACEUTICALS CORP COM NEW 00547W208 10115 1935961 SH DFND 0 1935961 0 ADVANCED ACCELERATOR APPLICATIONS SA SPONSORED ADS 00790T100 3556 52582 SH DFND 0 52582 0 AEGLEA BIO THERAPEUTICS INC COM 00773J103 639 129583 SH DFND 0 129583 0 AETNA INC COM 00817Y108 8034 50523 SH DFND 0 50523 0 AGIOS PHARMACEUTICALS INC PUT 00847X104 5547 83100 SH Put DFND 0 83100 0 ALNYLAM PHARMACEUTICALS INC COM 02043Q107 2376 20225 SH DFND 0 20225 0 ANTHEM INC COM 036752103 2548 13418 SH DFND 0 13418 0 ARENA PHARMACEUTICALS INC COM NEW 040047607 1838 72086 SH DFND 0 72086 0 AVADEL PHARMACEUTICALS PLC SPONSORED ADR 05337M104 960 91413 SH DFND 0 91413 0 AXOVANT SCIENCES LTD COM G0750W104 7698 1118894 SH DFND 0 1118894 0 AXOVANT SCIENCES LTD PUT G0750W104 25034 3638700 SH Put DFND 0 3638700 0 BIOGEN INC COM 09062X103 4869 15549 SH DFND 0 15549 0 CATALYST BIOSCIENCES INC COM NEW 14888D208 2133 421635 SH DFND 0 421635 0 CHEMOCENTRYX INC COM 16383L106 187 25182 SH DFND 0 25182 0 CYMABAY THERAPEUTICS INC COM 23257D103 605 75000 SH DFND 0 75000 0 DBV TECHNOLOGIES SA PUT 23306J101 772 18200 SH Put DFND 0 18200 0 EAGLE PHARMACEUTICALS INC COM 269796108 3807 63835 SH DFND 0 63835 0 EMERGENT BIOSOLUTIONS INC COM 29089Q105 3651 90268 SH DFND 0 90268 0 EVOLENT HEALTH INC CL A 30050B101 1399 78600 SH DFND 0 78600 0 FOAMIX PHARMACEUTICALS LTD SHS M46135105 773 139200 SH DFND 0 139200 0 GLAXOSMITHKLINE PLC SPONSORED ADR 37733W105 6971 171694 SH DFND 0 171694 0 GLAXOSMITHKLINE PLC CALL 37733W105 4060 100000 SH Call DFND 0 100000 0 GLOBUS MEDICAL INC CL A 379577208 4380 147364 SH DFND 0 147364 0 HALYARD HEALTH INC COM 40650V100 3914 86914 SH DFND 0 86914 0 ICON PLC SHS G4705A100 2688 23604 SH DFND 0 23604 0 INSMED INC PUT 457669307 8327 266800 SH Put DFND 0 266800 0 INTEGER HOLDINGS CORP COM 45826H109 2622 51258 SH DFND 0 51258 0 INTUITIVE SURGICAL INC PUT 46120E602 2615 2500 SH Put DFND 0 2500 0 KONINKLIJKE PHILIPS NV NY REG SH NEW 500472303 2795 67829 SH DFND 0 67829 0 KURA ONCOLOGY INC COM 50127T109 4122 275731 SH DFND 0 275731 0 LUMINEX CORP COM 55027E102 2358 115979 SH DFND 0 115979 0 MADRIGAL PHARMACEUTICALS INC COM 558868105 1213 26958 SH DFND 0 26958 0 MEDTRONIC PLC SHS G5960L103 4343 55844 SH DFND 0 55844 0 OASMIA PHARMACEUTICAL AB ADR 67421W109 211 203170 SH DFND 0 203170 0 OTONOMY INC COM 68906L105 328 100900 SH DFND 0 100900 0 OTONOMY INC PUT 68906L105 328 100900 SH Put DFND 0 100900 0 PFENEX INC COM 717071104 259 85867 SH DFND 0 85867 0 PROGENICS PHARMACEUTICALS INC COM 743187106 652 88523 SH DFND 0 88523 0 PUMA BIOTECHNOLOGY INC COM 74587V107 3260 27221 SH DFND 0 27221 0 QUOTIENT LTD SHS G73268107 11557 2344311 SH DFND 0 2344311 0 RIGEL PHARMACEUTICALS INC COM NEW 766559603 3971 1563307 SH DFND 0 1563307 0 SAGE THERAPEUTICS INC PUT 78667J108 11862 190400 SH Put DFND 0 190400 0 SANOFI SA SPONSORED ADR 80105N105 2245 45099 SH DFND 0 45099 0 SEATTLE GENETICS INC PUT 812578102 5441 100000 SH Put DFND 0 100000 0 STEADYMED LTD SHS M84920103 184 54950 SH DFND 0 54950 0 SUNESIS PHARMACEUTICALS INC COM PAR 867328700 65 33710 SH DFND 0 33710 0 UNITEDHEALTH GROUP INC COM 91324P102 2239 11430 SH DFND 0 11430 0 VERTEX PHARMACEUTICALS INC COM 92532F100 2261 14874 SH DFND 0 14874 0 VOCERA COMMUNICATIONS INC COM 92857F107 1760 56106 SH DFND 0 56106 0 XENCOR INC COM 98401F105 759 33100 SH DFND 0 33100 0 ZIMMER BIOMET HOLDINGS INC COM 98956P102 3634 31033 SH DFND 0 31033 0 ZOETIS INC PUT 98978V103 3188 50000 SH Put DFND 0 50000 0