The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| ADMA BIOLOGICS INC | Common Stock | 000899104 | 2,747 | 245,930 | SH | DFND | 0 | 245,930 | 0 | ||
| ADAMIS PHARMACEUTICALS CORP | Common Stock | 00547W208 | 7,210 | 1,168,566 | SH | DFND | 0 | 1,168,566 | 0 | ||
| ADVAXIS INC | Warrant | 007624208 | 161 | 39,000 | SH | DFND | 0 | 39,000 | 0 | ||
| ALMOST FAMILY INC | Common Stock | 020409108 | 5,669 | 195,807 | SH | DFND | 0 | 195,807 | 0 | ||
| AGILE THERAPEUTICS INC | Common Stock | 00847L100 | 4,604 | 749,887 | SH | DFND | 0 | 749,887 | 0 | ||
| BIODELIVERY SCIENCES INTL | Common Stock | 09060J106 | 4,472 | 372,043 | SH | DFND | 0 | 372,043 | 0 | ||
| BIOSCRIP INC | Common Stock | 09069N108 | 3,877 | 554,621 | SH | DFND | 0 | 554,621 | 0 | ||
| CARDINAL HEALTH INC | Common Stock | 14149Y108 | 5,013 | 62,100 | SH | DFND | 0 | 62,100 | 0 | ||
| CYMABAY THERAPEUTICS INC | Common Stock | 23257D103 | 1,198 | 121,900 | SH | DFND | 0 | 121,900 | 0 | ||
| CAREFUSION CORP | Common Stock | 14170T101 | 5,317 | 89,600 | SH | DFND | 0 | 89,600 | 0 | ||
| CELSUS THERAPEUTICS-SPON ADR | ADR | 15119A202 | 881 | 183,505 | SH | DFND | 0 | 183,505 | 0 | ||
| CONMED CORP | Common Stock | 207410101 | 2,252 | 50,100 | SH | DFND | 0 | 50,100 | 0 | ||
| COVIDIEN PLC | Common Stock | G2554F113 | 8,745 | 85,500 | SH | DFND | 0 | 85,500 | 0 | ||
| CTI BIOPHARMA CORP | Common Stock | 12648L106 | 1,192 | 505,000 | SH | DFND | 0 | 505,000 | 0 | ||
| ESPERION THERAPEUTICS INC | Common Stock | 29664W105 | 2,168 | 53,600 | SH | DFND | 0 | 53,600 | 0 | ||
| FORWARD PHARMA A/S-ADR | ADR | 34986J105 | 2,269 | 108,915 | SH | DFND | 0 | 108,915 | 0 | ||
| GLAXOSMITHKLINE PLC-SPON ADR | ADR | 37733W105 | 8,991 | 210,371 | SH | DFND | 0 | 210,371 | 0 | ||
| HARVARD APPARATUS REGENERATI | Common Stock | 41690A106 | 430 | 135,262 | SH | DFND | 0 | 135,262 | 0 | ||
| JOHNSON & JOHNSON | Common Stock | 478160104 | 4,183 | 40,000 | SH | DFND | 0 | 40,000 | 0 | ||
| MERIT MEDICAL SYSTEMS INC | Common Stock | 589889104 | 1,613 | 93,072 | SH | DFND | 0 | 93,072 | 0 | ||
| NANOSPHERE INC | Common Stock | 63009F105 | 2,112 | 5,386,213 | SH | DFND | 0 | 5,386,213 | 0 | ||
| ORTHOFIX INTERNATIONAL NV | Common Stock | N6748L102 | 2,345 | 78,007 | SH | DFND | 0 | 78,007 | 0 | ||
| ARATANA THERAPEUTICS INC | Common Stock | 03874P101 | 5,799 | 325,420 | SH | DFND | 0 | 325,420 | 0 | ||
| PFENEX INC | Common Stock | 717071104 | 4,026 | 560,765 | SH | DFND | 0 | 560,765 | 0 | ||
| QUOTIENT LTD | Common Stock | G73268107 | 21,831 | 1,212,850 | SH | DFND | 0 | 1,212,850 | 0 | ||
| REWALK ROBOTICS LTD | Common Stock | M8216Q101 | 1,127 | 59,707 | SH | DFND | 0 | 59,707 | 0 | ||
| SCYNEXIS INC | Common Stock | 811292101 | 1,722 | 172,581 | SH | DFND | 0 | 172,581 | 0 | ||
| SANOFI-ADR | ADR | 80105N105 | 11,836 | 259,500 | SH | DFND | 0 | 259,500 | 0 | ||
| SORRENTO THERAPEUTICS INC | Common Stock | 83587F202 | 1,860 | 184,720 | SH | DFND | 0 | 184,720 | 0 | ||
| TG THERAPEUTICS INC | Common Stock | 88322Q108 | 1,627 | 102,700 | SH | DFND | 0 | 102,700 | 0 | ||