X0306 5 2011-12-31 0 0 1 0001417926 INVO Bioscience, Inc. IVOB 0001479791 Ranoux Claude 8 CHESTNUT STREET WINCHESTER MA 01890 1 1 1 0 President INVO Bioscience Common Stock (Restricted) 2011-11-09 4 D 0 L 20000 0.017 D 24990183 D INVO Bioscience Common Stock (Restricted) 2011-11-10 4 D 0 L 13000 0.011 D 25977183 D INVO Bioscience Common Stock (Restricted) 2011-11-11 4 D 0 L 5000 0.011 D 25972183 D INVO Bioscience Common Stock (Restricted) 2011-11-14 4 D 0 L 75000 0.01 D 25897183 D INVO Bioscience Common Stock (Restricted) 2011-12-14 4 D 0 L 50000 0.01 D 25847183 D INVO Bioscience Common Stock (Restricted) 2011-12-16 4 D 0 L 45000 0.01 D 24802183 D INVO Bioscience Common Stock (Restricted) 2011-12-21 4 D 0 L 50000 0.01 D 24752183 D INVO Bioscience Common Stock (Restricted) 2011-12-28 4 D 0 L 42500 0.01 D 24709683 D INVO Bioscience Common Stock (Restricted) 2011-12-29 4 D 0 L 30000 0.01 D 24679683 D INVO Bioscience Common Stock (Restricted) 2011-12-30 4 D 0 L 60000 0.01 D 24619683 D I traded my securities on the public market using my agent, Morgan Stanley Smith Barney. Morgan Stanley was my agent until 03/29/2012, until my shares of INVO Bioscience were traded on the public market pursuant to rule 144. After March 2012, INVO Bioscience was delinquent as the company did not report to the SEC. Financial difficulties did not allow INVO Bioscience to pay the financial audits. From March 2012 until the 2 first quarters of 2017, the stock of INVO Bioscience was traded on the Pink Sheet. On 09/21/2011, I sold the last free trading shares (522,394 shares) I still owned from a pool of 840,000 free trading shares acquired in 2008. I also sold 691,790 restricted shares from a pool of 1,114,290 shares already issued to my agent to be traded on the public market. On December 31,2011, I owned 25,833,867 (2010) - 691,790 - 522,394 = 24,619,683 restricted shares. /s/ Claude Ranoux 2017-07-27