X0306 5 2018-12-31 0 0 0 0001417926 INVO Bioscience, Inc. ivob 0001479791 Ranoux Claude 8 CHESTNUT STREET WINCHESTER MA 01890 0 0 1 0 INVO BIOSCIENCE Common Stock 2018-02-21 5 S 0 28662 0.114 D 25344164 D INVO BIOSCIENCE Common Stock 2018-02-21 5 S 0 10000 0.112 D 25334164 D INVO BIOSCIENCE Common Stock 2018-02-21 5 S 0 5000 0.114 D 25329164 D INVO BIOSCIENCE Common Stock 2018-02-21 5 S 0 30300 0.12 D 25298864 D INVO BIOSCIENCE Common Stock 2018-02-23 5 S 0 100 0.18 D 25298764 D INVO BIOSCIENCE Common Stock 2018-02-28 5 S 0 2000 0.18 D 25296764 D INVO BIOSCIENCE Common Stock 2018-02-21 5 S 0 1000 0.12 D 25295764 D INVO BIOSCIENCE Common Stock 2018-03-05 5 S 0 12642 0.19 D 25283122 D INVO BIOSCIENCE Common Stock 2018-10-31 5 A 0 910878 0.0001 A 26194000 D INVO BIOSCIENCE Common Stock 2018-12-03 5 I 0 1000000 0.0001 D 25194000 D INVO BIOSCIENCE Common Stock 2018-12-03 5 S 0 500000 0.05 D 24694000 D Second Form-5 for year 2018 concerning the last 11 transactions that were not reported in the first Form-5 Claude Ranoux 2019-02-01