Revenue (Tables)

12 Months Ended

Dec. 31, 2022

Revenue [abstract]

Summary of Disaggregation of Revenue from Contracts with Customers

Disaggregation of revenue from contracts with customers is as follows:

	Year ended December 31,
	2022		2021		2020
	£000s		£000s		£000s
Revenue from Contracts with Customers
Research collaboration - Mallinckrodt plc		11,658		8,748		3,817
Research collaboration - AstraZeneca		5,081		2,652		22
Research collaboration - Other		184		623		1,414
Research collaboration - total		16,923		12,023		5,253
Royalties		578		392		226
Total revenue from contracts with customers		17,501		12,415		5,479