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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
$ in Thousands
9 Months Ended
Sep. 30, 2018
USD ($)
Sep. 30, 2017
USD ($)
Cash flows from operating activities:    
Net loss $ (41,519) $ (30,921)
Adjustments to reconcile net loss to cash used in operating activities:    
Depreciation 243 213
Amortization of right-of-use asset 283 265
Change in fair value of warrant liability   1,844
Amortization of debt discount 75 86
Stock-based compensation 6,417 2,070
Loss on disposal of fixed asset 9  
Change in operating assets and liabilities    
Prepaid expenses and other current assets (3,350) (732)
Inventory (910)  
Accounts payable (220) 74
Accrued expenses 1,143 (163)
Lease liabilities (295) (268)
Other long-term liabilities (8) (2)
Net cash used in operating activities (38,132) (27,534)
Cash flows from investing activities:    
Purchases of property and equipment (668) (198)
Net cash used in investing activities (668) (198)
Cash flows from financing activities:    
Proceeds from common stock offering, net of underwriters discounts   96,255
Proceeds from venture debt, net of debt issuance costs of $50 and $0 2,728 10,000
Payment of principal on venture debt (1,667)  
Payment of common stock offering costs   (2,111)
Payment of deferred offering costs (163)  
Proceeds from exercise of stock options 291 189
Net cash provided by financing activities 1,189 104,333
Net (decrease) increase in cash and restricted cash (37,611) 76,601
Cash and restricted cash at beginning of period 114,699 45,581
Cash and restricted cash at end of period 77,088 122,182
Reconciliation of cash and restricted cash:    
Cash and restricted cash at end of period 77,088 122,182
Less restricted cash (2,178) (133)
Cash at end of period 74,910 122,049
Non-cash investing and financing activities:    
Conversion of convertible preferred stock into common stock   118,391
Reclassification of warrants to additional paid-in capital   2,883
Common stock offering cost included in accounts payable and accrual   131
Purchases of property and equipment in accounts payable 110 45
Supplemental disclosure:    
Cash paid for interest $ 1,138 $ 532