CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) $ in Thousands	3 Months Ended	9 Months Ended
Sep. 30, 2018	Sep. 30, 2017	Sep. 30, 2018	Sep. 30, 2017
Operating expenses:
Research and development	$ 7,027	$ 7,018	$ 20,051	$ 23,128
General and administrative	8,469	2,516	21,102	5,607
Total operating expenses	15,496	9,534	41,153	28,735
Loss from operations	(15,496)	(9,534)	(41,153)	(28,735)
Other income (expense):
Interest income	325	194	848	276
Interest expense	(432)	(212)	(1,214)	(618)
Change in fair value of warrant liability		(623)		(1,844)
Total other income (expense)	(107)	(641)	(366)	(2,186)
Net loss	$ (15,603)	$ (10,175)	$ (41,519)	$ (30,921)
Net loss per share—basic and diluted	$ (0.63)	$ (0.56)	$ (1.69)	$ (4.51)
Weighted average shares outstanding—basic and diluted	24,600,080	18,034,278	24,570,081	6,860,777

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