144 0001415537 XXXXXXXX LIVE 0001479419 KALA BIO, INC. 001-38150 1167 MASSACHUSETTS AVENUE ARLINGTON MA 02476 781-996-5252 Mark T Iwicki Director Common Stock ETRADE FINANCIAL CORPORATION

3 EDISON DRIVE ALPHARETTA GA 30005

13227 53040.27 6452398 06/24/2025 NASDAQ Common Stock 06/24/2025 Restricted Stock Unit Vesting Issuer N 52952 06/24/2025 Equity Compensation N Mark T Iwick

1167 MASSACHUSETTS AVENUE ARLINGTON MA 02476

Common Stock 06/03/2025 10866 40638.84 Represents the sale of shares of common stock pursuant to a "sell-to-cover" transaction in order to satisfy tax withholding obligations in connection with the vesting of RSUs previously granted to the Reporting Person. This sale was effected pursuant to an automatic sell-to-cover instruction effected pursuant to Rule 10b5-1 adopted by the Reporting Person on November 9, 2020 and does not represent a discretionary sale by the Reporting Person. 06/24/2025 /s/ Mary Reumuth, Attorney-in-Fact