X0303 4 2011-02-02 0001333763 Chelsea Therapeutics International, Ltd. CHTP 0001458177 VENROCK HEALTHCARE CAPITAL PARTNERS LP C/O VENROCK 3340 HILLVIEW AVENUE PALO ALTO CA 94304 0 0 1 0 0001479354 VHCP Co-Investment Holdings, LLC C/O VENROCK 3340 HILLVIEW AVENUE PALO ALTO CA 94304 0 0 1 0 0001479355 VHCP Management, LLC C/O VENROCK 3340 HILLVIEW AVENUE PALO ALTO CA 94304 0 0 1 0 0001365618 Hove Anders D C/O VENROCK 530 FIFTH AVENUE, 22ND FLOOR NEW YORK NY 10036 0 0 1 0 0001239242 ROBERTS BRYAN E C/O VENROCK 3340 HILLVIEW AVENUE PALO ALTO CA 94304 0 0 1 0 Common Stock 2011-02-02 4 P 0 75000 4.9999 A 5189934 I By Fund Consists of 4,387,367 shares of common stock held directly by Venrock Healthcare Capital Partners, L.P. ("VHCP") and 802,567 shares of common stock held directly by VHCP Co-Investment Holdings, LLC ("VHCP Co-Investment"). VHCP Management, LLC ("VHCP Management") is the general partner of VHCP and VHCP Co-Investment and may be deemed to beneficially own these shares. Messrs. Anders Hove and Bryan Roberts are the managing members of VHCP Management and may be deemed to beneficially own these shares. Each reporting person disclaims beneficial ownership of these shares, except to the extent of his or its respective pecuniary interest therein. /s/ David L. Stepp, Authorized Signatory 2011-02-04 /s/ David L. Stepp, Authorized Signatory 2011-02-04 /s/ David L. Stepp, Authorized Signatory 2011-02-04 /s/ David L. Stepp, as attorney-in-fact 2011-02-04 /s/ David L. Stepp, as attorney-in-fact 2011-02-04