SEC Form 3

FORM 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person* VENROCK HEALTHCARE CAPITAL PARTNERS LP (Last) (First) (Middle) C/O VENROCK 3340 HILLVIEW AVENUE (Street) PALO ALTO CA 94304 (City) (State) (Zip)	2. Date of Event Requiring Statement (Month/Day/Year) 11/30/2010	3. Issuer Name and Ticker or Trading Symbol Anacor Pharmaceuticals Inc [ ANAC ]
		4. Relationship of Reporting Person(s) to Issuer (Check all applicable) Director 10% Owner Officer (give title below) X Other (specify below) See footnote 2	5. If Amendment, Date of Original Filed (Month/Day/Year)
			6. Individual or Joint/Group Filing (Check Applicable Line) Form filed by One Reporting Person X Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1. Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)
Common Stock	2,000,000	I	By Fund(1)(2)

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

1. Name and Address of Reporting Person* VENROCK HEALTHCARE CAPITAL PARTNERS LP (Last) (First) (Middle) C/O VENROCK 3340 HILLVIEW AVENUE (Street) PALO ALTO CA 94304 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director 10% Owner Officer (give title below) X Other (specify below) See footnote 2

1. Name and Address of Reporting Person* VHCP Co-Investment Holdings, LLC (Last) (First) (Middle) C/O VENROCK 3340 HILLVIEW AVENUE (Street) PALO ALTO CA 94304 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director 10% Owner Officer (give title below) X Other (specify below) See footnote 2

1. Name and Address of Reporting Person* VHCP Management, LLC (Last) (First) (Middle) C/O VENROCK 3340 HILLVIEW AVENUE (Street) PALO ALTO CA 94304 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director 10% Owner Officer (give title below) X Other (specify below) See footnote 2

1. Name and Address of Reporting Person* ROBERTS BRYAN E (Last) (First) (Middle) C/O VENROCK 3340 HILLVIEW AVENUE (Street) PALO ALTO CA 94304 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director 10% Owner Officer (give title below) X Other (specify below) See footnote 2

Explanation of Responses:

1. 1,690,722 shares of common stock are held directly by Venrock Healthcare Capital Partners, L.P. ("VHCP"). 309,278 shares of common stock are held directly by Venrock Co-Investment Holdings, LLC ("Venrock Co-Investment"). VHCP Management, LLC ("VHCP Management") is the general partner of VHCP and the manager of Venrock Co-Investment and may be deemed to beneficially own these shares. Messrs. Anders Hove and Bryan Roberts are the managing members of VHCP Management and may be deemed to beneficially own these shares. Dr. Hove is a director of the issuer and files separate Section 16 reports. Mr. Roberts and VHCP Management disclaim beneficial ownership of these shares, except to the extent of their respective indirect pecuniary interests therein.

2. The reporting persons may be deemed members of a Section 13(d) group owning more than 10% of the Issuer's shares of common stock.

Remarks:

	/s/ David L. Stepp, Authorized Signatory	12/02/2010
	/s/ David L. Stepp, Authorized Signatory	12/02/2010
	/s/ David L. Stepp, Authorized Signatory	12/02/2010
	/s/ David L. Stepp, as attorney-in-fact	12/02/2010
	** Signature of Reporting Person	Date
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