13F-HR LIVE false true false 0001478735 XXXXXXXX 03-31-2021 03-31-2021 false TWO SIGMA ADVISERS, LP

100 Avenue of the Americas 16th Floor New York NY 10013

13F HOLDINGS REPORT 028-14367 Y This Form 13F holdings report is being filed on behalf of Two Sigma Advisers, LP ("Advisers"). Advisers serves as the sole manager or investment manager, as applicable, of (i) Two Sigma U.S. All Cap Core Equity Fund, LP ("All Cap"), Two Sigma Absolute Return Portfolio, LLC ("Absolute Return"), Two Sigma Active Extension U.S. All Cap Equity Portfolio, LLC ("Active Extension All Cap"), Two Sigma Active Extension U.S. Small Cap Equity Fund, LP ("Active Extension Small Cap"), Two Sigma Macro Portfolio, LLC ("Macro"), Two Sigma World Core Fund, LP ("World Core") and Two Sigma Equity Risk Premia Portfolio, LLC ("Equity Risk Premia"), seven investment entities that are managed by Advisers, each of which may be deemed to be an "other manager" for purposes of this Form 13F report, (ii) Two Sigma International Core Portfolio, LLC ("International Core"), an investment entity that is managed by Advisers and that may not presently be deemed to be an "other manager" for purposes of this Form 13F report and (iii) one or more separately managed accounts and subadvised accounts (collectively, the "Managed Accounts"), each of which may not presently be deemed to be an "other manager" for purposes of this 13F report. Advisers, rather than All Cap, Absolute Return, Active Extension All Cap, Active Extension Small Cap, Macro, World Core, Equity Risk Premia, International Core or the Managed Accounts, exercises sole investment discretion and voting authority over the securities held in the various accounts of All Cap, Absolute Return, Active Extension All Cap, Active Extension Small Cap, Macro, World Core, Equity Risk Premia, International Core and in the Managed Accounts. Matthew B. Siano, Esq. 212-625-5700 /s/ Matthew B. Siano, Esq. New York NY 05-17-2021 7 2526 36399119 1 0001507209 028-14405 Two Sigma U.S. All Cap Core Equity Fund, LP 2 0001569734 028-15367 TWO SIGMA ABSOLUTE RETURN PORTFOLIO, LLC 3 0001569731 028-15404 TWO SIGMA ACTIVE EXTENSION U.S. ALL CAP EQUITY PORTFOLIO, LLC 4 0001559804 028-15364 Two Sigma Active Extension U.S. Small Cap Equity Fund, LP 5 0001634034 028-16751 Two Sigma Macro Portfolio, LLC 6 0001630305 028-17350 Two Sigma World Core Fund, LP 7 0001667002 028-17346 Two Sigma Equity Risk Premia Portfolio, LLC