144/A 0001950047-25-009206 0001780854 XXXXXXXX LIVE 0001478320 Adaptive Biotechnologies Corp 001-38957 1165 EASTLAKE AVE E SEATTLE WA 98109 206-659-0067 BENZENO SHARON Officer Common Morgan Stanley Smith Barney LLC Executive Financial Services

1 New York Plaza 8th Floor New York NY 10004

308477 5034344.64 152665188 11/21/2025 NASDAQ Common 11/21/2025 Exercise of Stock Options Issuer N 308477 11/21/2025 Cash N 10b5-1 Sales for SHARON BENZENO

1165 Eastlake Avenue Seattle WA 98109

Common 11/20/2025 297925 4928722.24 The Form 144 was amended to update the amount sold on 11/21/2025. 11/24/2025 08/18/2025 /s/ Sharon Benzeno