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Equity Incentive Plans - Additional Information (Details) - USD ($)
$ / shares in Units, $ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Weighted-average remaining contractual life options outstanding 7 years    
Weighted-average remaining contractual life vested and exercisable options outstanding 5 years 8 months 12 days    
Weighted-average grant date fair value $ 24.22 $ 21.11 $ 6.87
Total intrinsic value of options exercised $ 156,500 $ 190,400 $ 39,100
Proceeds from exercise of stock options 26,717 21,748 $ 4,055
Proceeds from settlement of stock option exercised in prior periods 300 $ 500  
Unrecognized share-based compensation expense related to unvested stock options $ 96,800    
Unrecognized share-based compensation expense related to unvested stock options, weighted-average period for recognition 2 years 10 months 24 days    
Option Valuation Model      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Expected dividend yield 0.00%    
Restricted Stock Units (RSUs)      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Unrecognized share-based compensation expense related to unvested stock options, weighted-average period for recognition 3 years 4 months 24 days    
Unrecognized share-based compensation expense related to unvested RSUs $ 38,300    
Sequenta 2008 Stock Plan      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Shares available for future issuance 0    
Equity awards outstanding 0    
2009 Equity Incentive Plan | Grant      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Shares available for future issuance 0    
2009 Equity Incentive Plan | Grant | Maximum      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Option expiration period 10 years    
2019 Equity Incentive Plan      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Shares available for future issuance 22,299,923 18,617,001  
2019 Equity Incentive Plan | Grant      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Number of shares authorized for issuance 29,131,628    
2019 Equity Incentive Plan | Grant | Non Employee Directors      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Vesting period 4 years    
2019 Equity Incentive Plan | Grant | Maximum      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Option expiration period 10 years    
2019 Equity Incentive Plan | Restricted Stock Units (RSUs)      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Weighted-average grant date fair value $ 37.98 $ 28.10 $ 41.63