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Condensed Consolidated Statements of Shareholders' Equity (Unaudited) - USD ($)
$ in Thousands
Total
Common Stock
Additional Paid In Capital
Accumulated Other Comprehensive Gain (Loss)
Accumulated Deficit
Noncontrolling Interest
Beginning Balance at Dec. 31, 2020 $ 743,266 $ 14 $ 1,253,971 $ 893 $ (511,612)  
Beginning Balance, Shares at Dec. 31, 2020   137,646,896        
Issuance of common stock upon exercise of common stock warrant, Shares   54,162        
Issuance of common stock for cash upon exercise of stock options 23,299   23,299      
Issuance of common stock for cash upon exercise of stock options, Shares   3,310,804        
Vesting of restricted stock units   15,625        
Common stock option, restricted stock unit and market-based restricted stock unit share-based compensation 31,376   31,376      
Capital contributions for Digital Biotechnologies, Inc. 429   300     $ 129
Other comprehensive loss (886)     (886)    
Net loss (145,941)       (145,846) (95)
Ending Balance at Sep. 30, 2021 651,543 $ 14 1,308,946 7 (657,458) 34
Ending Balance, Shares at Sep. 30, 2021   141,027,487        
Beginning Balance at Jun. 30, 2021 693,310 $ 14 1,294,506 216 (601,555) 129
Beginning Balance, Shares at Jun. 30, 2021   140,663,755        
Issuance of common stock for cash upon exercise of stock options 2,797   2,797      
Issuance of common stock for cash upon exercise of stock options, Shares   360,607        
Vesting of restricted stock units   3,125        
Common stock option, restricted stock unit and market-based restricted stock unit share-based compensation 11,643   11,643      
Other comprehensive loss (209)     (209)    
Net loss (55,998)       (55,903) (95)
Ending Balance at Sep. 30, 2021 651,543 $ 14 1,308,946 7 (657,458) 34
Ending Balance, Shares at Sep. 30, 2021   141,027,487        
Beginning Balance at Dec. 31, 2021 604,102 $ 14 1,324,006 (1,137) (718,891) 110
Beginning Balance, Shares at Dec. 31, 2021   141,393,865        
Issuance of common stock for cash upon exercise of stock options $ 7,562   7,562      
Issuance of common stock for cash upon exercise of stock options, Shares 1,361,891 1,361,891        
Vesting of restricted stock units   231,371        
Common stock option, restricted stock unit and market-based restricted stock unit share-based compensation $ 41,183   41,183      
Other comprehensive loss (4,834)     (4,834)    
Net loss (160,199)       (160,063) (136)
Ending Balance at Sep. 30, 2022 487,814 $ 14 1,372,751 (5,971) (878,954) (26)
Ending Balance, Shares at Sep. 30, 2022   142,987,127        
Beginning Balance at Jun. 30, 2022 518,316 $ 14 1,357,763 (5,800) (833,673) 12
Beginning Balance, Shares at Jun. 30, 2022   142,784,868        
Issuance of common stock for cash upon exercise of stock options 846   846      
Issuance of common stock for cash upon exercise of stock options, Shares   131,802        
Vesting of restricted stock units   70,457        
Common stock option, restricted stock unit and market-based restricted stock unit share-based compensation 14,142   14,142      
Other comprehensive loss (171)     (171)    
Net loss (45,319)       (45,281) (38)
Ending Balance at Sep. 30, 2022 $ 487,814 $ 14 $ 1,372,751 $ (5,971) $ (878,954) $ (26)
Ending Balance, Shares at Sep. 30, 2022   142,987,127