201 Broadway Cambridge, MA 02139 www.iqvia.com

September 29, 2022

VIA EDGAR

Christopher Dunham

Amanda Ravitz

United States Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, D.C. 20549

            RE:      IQVIA Holdings Inc.

                        Definitive Proxy Statement on Schedule 14A

Filed February 28, 2022

File No. 001-35907

Dear Mr. Dunham and Ms. Ravitz,

The purpose of this letter is to respond to your letter of September 19, 2022 (the “Letter”).

I am writing to confirm that, to the extent applicable, IQVIA Holdings Inc. (the “Company”) will enhance its future proxy statement disclosure in accordance with the topics discussed in the Letter as well as with respect to any material developments to the Company’s risk oversight structure, in each case, in accordance with Item 407(h) of Regulation S-K.

Sincerely,

IQVIA Holdings Inc.
	By:	/s/ Eric Sherbet
		Eric Sherbet
		Executive Vice President, General Counsel and Secretary
cc:	Ari Bousbib, Chairman, Chief Executive Officer and President
	IQVIA Holdings Inc.
	Lyuba A. Goltser, Partner
	Weil, Gotshal & Manges LLP