-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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 d+sZbxFFFwhOuI0C+ZLIAA==

<SEC-DOCUMENT>0001478242-09-000002.txt : 20091218
<SEC-HEADER>0001478242-09-000002.hdr.sgml : 20091218
<ACCEPTANCE-DATETIME>20091218112157
ACCESSION NUMBER:		0001478242-09-000002
CONFORMED SUBMISSION TYPE:	D
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20091218
DATE AS OF CHANGE:		20091218
EFFECTIVENESS DATE:		20091218

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Quintiles Transnational Holdings Inc.
		CENTRAL INDEX KEY:			0001478242
		IRS NUMBER:				271341991
		STATE OF INCORPORATION:			NC
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		D
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-137023
		FILM NUMBER:		091249010

	BUSINESS ADDRESS:	
		STREET 1:		4820 EMPEROR BLVD.
		CITY:			DURHAM
		STATE:			NC
		ZIP:			27703
		BUSINESS PHONE:		919-998-2000

	MAIL ADDRESS:	
		STREET 1:		4820 EMPEROR BLVD.
		CITY:			DURHAM
		STATE:			NC
		ZIP:			27703
</SEC-HEADER>
<DOCUMENT>
<TYPE>D
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0603</schemaVersion>

    <submissionType>D</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001478242</cik>
        <entityName>Quintiles Transnational Holdings Inc.</entityName>
        <issuerAddress>
            <street1>4820 EMPEROR BLVD.</street1>
            <city>DURHAM</city>
            <stateOrCountry>NC</stateOrCountry>
            <zipCode>27703</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>919-998-2000</issuerPhoneNumber>
        <jurisdictionOfInc>NORTH CAROLINA</jurisdictionOfInc>
        <issuerPreviousNameList>
            <previousName>QPB Holdings Corp.</previousName>
        </issuerPreviousNameList>
        <edgarPreviousNameList>
            <value>None</value>
        </edgarPreviousNameList>
        <entityType>Corporation</entityType>
        <yearOfInc>
            <withinFiveYears>true</withinFiveYears>
            <value>2009</value>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Dennis</firstName>
                <middleName>B</middleName>
                <lastName>Gillings</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>4820 Emperor Blvd</street1>
                <city>Durham</city>
                <stateOrCountry>NC</stateOrCountry>
                <zipCode>27703</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>John</firstName>
                <middleName>D.</middleName>
                <lastName>Ratliff</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>4820 Emperor Blvd</street1>
                <city>Durham</city>
                <stateOrCountry>NC</stateOrCountry>
                <zipCode>27703</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Mr. Ratliff became an executive officer of the issuer upon the completion of the share exchange.</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Fred</firstName>
                <lastName>Cohen</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>301 Commerce Street</street1>
                <street2>Suite 3300</street2>
                <city>Fort Worth</city>
                <stateOrCountry>TX</stateOrCountry>
                <zipCode>76102</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>John</firstName>
                <lastName>Connaughton</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>111 Huntington Ave.</street1>
                <city>Boston</city>
                <stateOrCountry>MA</stateOrCountry>
                <zipCode>02199</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Jonathan</firstName>
                <middleName>J.</middleName>
                <lastName>Coslet</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>301 Commerce Street</street1>
                <street2>Suite 3300</street2>
                <city>Fort Worth</city>
                <stateOrCountry>TX</stateOrCountry>
                <zipCode>76102</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Ronald</firstName>
                <middleName>J.</middleName>
                <lastName>Wooten</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>4820 Emperor Blvd.</street1>
                <city>Durham</city>
                <stateOrCountry>NC</stateOrCountry>
                <zipCode>27703</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Mr. Wooten became an executive officer of the issuer upon the completion of the share exchange.</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Christopher</firstName>
                <lastName>Gordon</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>111 Huntington Ave.</street1>
                <city>Boston</city>
                <stateOrCountry>MA</stateOrCountry>
                <zipCode>02199</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Jack</firstName>
                <lastName>Greenberg</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>4820 Emperor Blvd.</street1>
                <city>Durham</city>
                <stateOrCountry>NC</stateOrCountry>
                <zipCode>27703</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>John</firstName>
                <lastName>Moore</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>375 Park Avenue</street1>
                <street2>Suite 3001</street2>
                <city>New York</city>
                <stateOrCountry>NY</stateOrCountry>
                <zipCode>10152</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Leonard</firstName>
                <lastName>Schaeffer</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>301 Commerce Street</street1>
                <street2>Suite 3300</street2>
                <city>Fort Worth</city>
                <stateOrCountry>TX</stateOrCountry>
                <zipCode>76102</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Tan</firstName>
                <middleName>Suan</middleName>
                <lastName>Swee</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>60 B. Orchard Road #06-18, Tower 2</street1>
                <street2>The Atrium at Orchard</street2>
                <city>Singapore</city>
                <stateOrCountry>U0</stateOrCountry>
                <zipCode>238891</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Other Health Care</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Decline to Disclose</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>false</isAmendment>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2009-12-14</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isEquityType>true</isEquityType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>true</isBusinessCombinationTransaction>
            <clarificationOfResponse>This offering is made in connection with a holding company formation through a 1:1 statutory share exchange.</clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>0</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>3225011208</totalOfferingAmount>
            <totalAmountSold>3225011208</totalAmountSold>
            <totalRemaining>0</totalRemaining>
            <clarificationOfResponse>No cash consideration was paid in the share exchange.  Because there is no public trading market for the issuer's common stock, the amounts listed above are based on the issuer's good faith estimate of the value of its shares.</clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>49</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse></clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
            </grossProceedsUsed>
            <clarificationOfResponse></clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>Quintiles Transnational Holdings Inc.</issuerName>
                <signatureName>Beverly Rubin</signatureName>
                <nameOfSigner>Beverly Rubin</nameOfSigner>
                <signatureTitle>Assistant Secretary</signatureTitle>
                <signatureDate>2009-12-18</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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