X0306 4/A 2017-03-01 2017-03-02 0 0001478121 Pfenex Inc. PFNX 0001612843 Lucy Patrick K. C/O PFENEX INC., 10790 ROSELLE STREET SAN DIEGO CA 92121 0 1 0 0 See Remarks Stock Option (right to buy) 7.47 2017-03-01 4 A 0 11238 0.00 A 2027-03-01 Common Stock 11238 11238 D This amendment is being filed to correct the total number of derivative securities acquired in connection with the Option. 1/24th of the total shares subject to the Option shall vest every month after the date of grant such that all shares shall be fully vested on the two year anniversary of the Vesting Commencement Date. "Vesting Commencement Date" shall mean March 1, 2017. Interim CEO, President and Secretary, and Chief Business Officer /s/ Patricia Lady, as Attorney-in-Fact 2017-03-16