X0306 4 2017-03-01 0 0001478121 Pfenex Inc. PFNX 0001622297 Chen Hubert C C/O PFENEX INC., 10790 ROSELLE STREET SAN DIEGO CA 92121 0 1 0 0 Chief Medical Officer Stock Option (right to buy) 7.47 2017-03-01 4 A 0 85000 0.00 A 2027-03-01 Common Stock 85000 85000 D 25% shall vest on the one year anniversary of the Vesting Commencement Date and 1/48th of the total shares subject to the Option shall vest every month thereafter such that all shares shall be fully vested on the four year anniversary of the Vesting Commencement Date. "Vesting Commencement Date" shall mean March 1, 2017. /s/ Patricia Lady, as Attorney-in-Fact 2017-03-02