X0306 4 2017-03-01 0 0001478121 Pfenex Inc. PFNX 0001612843 Lucy Patrick K. C/O PFENEX INC., 10790 ROSELLE STREET SAN DIEGO CA 92121 0 1 0 0 See Remarks Stock Option (right to buy) 7.47 2017-03-01 4 A 0 85000 0.00 A 2027-03-01 Common Stock 85000 85000 D Stock Option (right to buy) 7.47 2017-03-01 4 A 0 85000 0.00 A 2027-03-01 Common Stock 11238 11238 D 25% shall vest on the one year anniversary of the Vesting Commencement Date and 1/48th of the total shares subject to the Option shall vest every month thereafter such that all shares shall be fully vested on the four year anniversary of the Vesting Commencement Date. "Vesting Commencement Date" shall mean March 1, 2017. 1/24th of the total shares subject to the Option shall vest every month after the date of grant such that all shares shall be fully vested on the two year anniversary of the Vesting Commencement Date. "Vesting Commencement Date" shall mean March 1, 2017. Interim CEO, President and Secretary /s/ Patricia Lady, as Attorney-in-Fact 2017-03-02