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Income Taxes - Reconciliation of income tax provision (benefit) (Details) - USD ($)
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Income Taxes    
Federal provision (benefit) for income taxes $ 0 $ 0
State provision (benefit) for income taxes 0 0
Reconciliation, amount    
Federal income tax benefit at statutory rate (6,059,381) (5,163,979)
State and local tax, net of federal benefit 0  
Tax credits    
Research and development credit (1,625,304) (1,065,647)
Change in valuation allowance 7,460,209 6,127,570
Nontaxable or Nondeductible Items    
Stock-based compensation 252,715 81,012
Change in fair value of warrants (29,820) (372,268)
Nondeductible compensation 0 392,495
Other 1,581 $ 817
Income Tax Expense (Benefit), Total $ 0  
Reconciliation, percent    
Federal income tax benefit at statutory rate 21.00% 21.00%
State and local tax, net of federal benefit 0.00% 0.00%
Tax credits    
Research and development credit 5.60% 4.30%
Change in valuation allowance (25.80%) (24.90%)
Nontaxable or Nondeductible Items    
Stock-based compensation (0.90%) (0.30%)
Change in fair value of warrants 0.10% 1.50%
Nondeductible compensation 0.00% (1.60%)
Other 0.00% 0.00%
Effective income tax rate 0.00% 0.00%