Net Loss Per Share (Details) - USD ($) $ / shares in Units, $ in Thousands	12 Months Ended
Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Basic and diluted net loss per share:
Net loss	$ (74,216)	$ (58,020)	$ (17,037)
Preferred stock dividends			(2,920)
Accretion of preferred stock			(168)
Net loss	$ (74,216)	$ (58,020)	$ (20,125)
Weighted-average shares used to compute basic and diluted net loss per share	42,330,908	19,917,348	1,962,845
Net loss per share, basic and diluted	$ (1.75)	$ (2.91)	$ (10.25)
Stock options
Net Loss per Share
Antidilutive securities (in shares)	6,800,000
Common stock warrants
Net Loss per Share
Antidilutive securities (in shares)	400,000
ESPP
Net Loss per Share
Antidilutive securities (in shares)	100,000

Securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) or earnings per unit (EPU) in the future that were not included in the computation of diluted EPS or EPU because to do so would increase EPS or EPU amounts or decrease loss per share or unit amounts for the period presented.

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