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Common Stock and Stockholders' Equity (Deficit) - Stock Plan and Stock Options (Details) - USD ($)
$ / shares in Units, $ in Thousands
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Shares Available for Grant        
Balance, beginning of period (in shares) 1,986,390 741,971 694,280  
Increase in Plan authorized shares 1,937,770 2,493,337 1,621,795  
Stock options grants (in shares) (3,910,431) (1,522,581) (1,574,104)  
Stock options cancelled (in shares)   240,064    
Stock options expired (in shares) 329,487 33,599    
Balance, end of period (in shares) 343,216 1,986,390 741,971 694,280
Number of Shares Outstanding        
Balance, beginning of period (in shares) 3,853,479 2,875,106 2,115,069  
Stock option grants (in shares) 3,910,431 1,522,581 1,574,104  
Stock option exercised (in shares) (594,555) (270,545) (786,074)  
Stock options cancelled (in shares)   (240,064) (27,993)  
Stock options expired (in shares) (329,487) (33,599)    
Balance, end of period (in shares) 6,839,868 3,853,479 2,875,106 2,115,069
Vested or expected to vest at end of period (in shares) 6,199,485      
Exercisable as of end of period (in shares) 1,604,209      
Weighted-Average Exercise Price        
Balance, beginning of period (in dollars per share) $ 7.62 $ 3.73 $ 1.14  
Stock option grants (in dollars per share) 14.58   5.53  
Stock option exercised (in dollars per share) 4.29   0.96  
Stock options cancelled (in dollars per share)     1.60  
Stock options expired (in dollars per share) 11.62      
Balance, end of period (in dollars per share) 11.70 $ 7.62 $ 3.73 $ 1.14
Vested or expected to vest at end of period (in dollars per share) 11.38      
Exercisable as of end of period (in dollars per share) $ 6.08      
Weighted-average remaining contractual life in Years        
Weighted-average remaining contractual life (in years) 8 years 7 months 21 days 8 years 6 months 15 days 8 years 4 months 17 days 8 years 3 months 11 days
Vested or expected to vest at end of period (in years) 8 years 6 months 18 days      
Exercisable as of end of period (in years) 7 years 2 months 12 days      
Aggregate Intrinsic Value        
Aggregate Intrinsic Value $ 36,795 $ 41,894 $ 6,758 $ 4,058
Stock option grants 519      
Stock options exercised 6,984      
Stock options expired 1,699      
Vested or expected to vest at end of period 35,426      
Exercisable as of end of period 17,505      
Grant-date fair value of stock options granted during the period $ 25,900 $ 10,800 $ 4,800  
Fair value assumptions        
Volatility, minimum (as a percent) 44.70% 45.40% 53.30%  
Volatility, maximum (as a percent) 47.80% 51.00% 53.70%  
Expected life (in years) 6 years 6 years 10 months 24 days 7 years  
Risk-free interest rate, minimum 1.09% 1.85% 1.92%  
Risk-free interest rate, maximum 2.29% 2.06% 2.30%  
Maximum        
Stock-based Awards        
Exercisable period (in years) 10 years      
Weighted Average        
Fair value assumptions        
Weighted-average fair value of underlying common stock $ 6.63 $ 7.09 $ 5.53