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Common Stock and Stockholders' Equity (Deficit) - Warrants (Details)
1 Months Ended 12 Months Ended
Dec. 09, 2016
$ / shares
shares
Dec. 22, 2015
$ / shares
shares
Jul. 24, 2015
item
$ / shares
shares
May 02, 2014
USD ($)
item
$ / shares
shares
Jul. 31, 2016
USD ($)
item
$ / shares
shares
Dec. 31, 2016
USD ($)
Dec. 31, 2015
USD ($)
Dec. 31, 2014
USD ($)
Warrants                
Fair value of warrants issued, resulting in an increase to additional paid in capital | $           $ 7,717,000   $ 219,000
Non-cash fair value adjustment of warrants | $           7,717,000 $ 798,000  
Common stock warrants                
Warrants                
Number of shares issued upon exercise of warrants   54,830            
Cashless exercise of warrants (in shares)   65,619            
Exercise price of warrants (in dollars per share) | $ / shares   $ 2.95            
Affiliates of SVB | Common stock warrants                
Warrants                
Number of warrants issued       131,239 798,694      
Number of shares that may be exercised from warrants       131,239 798,694      
Number of shares issued upon exercise of warrants 107,931   59,281          
Cashless exercise of warrants (in shares) 399,347   65,620          
Exercise price of warrants (in dollars per share) | $ / shares $ 13.50   $ 2.95 $ 2.95 $ 13.50      
Number of affiliates of lender granted warrants | item     1 2 2      
Term of warrants       10 years 10 years      
Warrants outstanding | $       $ 200,000   $ 399,347    
Fair value of warrants issued, resulting in an increase to additional paid in capital | $         $ 7,700,000