NET LOSS PER SHARE (Details) - shares	Dec. 31, 2021	Dec. 31, 2020
NET LOSS PER SHARE
Stock options	4,963,545	7,366,420
Warrants	16,117,343	16,531,825
Accrued stock payable	1,769,537	359,415
Convertible notes	5,785,450	2,261,538
Preferred stock	1,180,000
Possibly dilutive equity instruments	29,815,875	26,519,198