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Summary of Significant Accounting Policies - Narrative (Details)
1 Months Ended 3 Months Ended 6 Months Ended 9 Months Ended 12 Months Ended 67 Months Ended 79 Months Ended
Jan. 07, 2020
USD ($)
Dec. 31, 2019
USD ($)
Oct. 31, 2018
shares
Oct. 31, 2017
USD ($)
May 31, 2017
USD ($)
Jun. 30, 2016
USD ($)
Sep. 30, 2022
USD ($)
Jun. 30, 2022
USD ($)
Jun. 30, 2022
USD ($)
Sep. 30, 2022
USD ($)
Dec. 31, 2022
USD ($)
segment
shares
Dec. 31, 2021
USD ($)
shares
Dec. 31, 2022
USD ($)
Dec. 31, 2022
USD ($)
Sep. 15, 2022
USD ($)
Sep. 30, 2018
Overstatement of net loss               $ 3,300,000 $ 3,300,000 $ 3,300,000            
Income tax expense (benefit)                     $ (215,937) $ (145,974)        
Accumulated deficit             $ (193,929,176) (180,670,826) (180,670,826) (193,929,176) 209,153,659 165,718,953 $ 209,153,659 $ 209,153,659    
Net loss             13,347,771 $ 6,937,910 $ 15,127,708 28,475,479 43,862,197 35,400,807        
Cash, cash equivalents and short term investments                     $ 39,000,000.0   39,000,000.0 39,000,000.0    
Derivative warrant liability                       11,020        
Number of operating segments | segment                     1          
Cash balance insured                     $ 250,000 250,000 250,000 250,000    
Cash balance uninsured                     7,800,000   7,800,000 7,800,000    
Unrecognized tax benefit                     0 0 0 0    
Revenue                     370,176 2,112,806        
Allowable expenses incurred under NIH grant                     40,000.00 $ 30,000.00        
Customer deposits                     $ 1,600,000   $ 1,600,000 $ 1,600,000    
Shattuck                                
License fee received           $ 50,000                    
Pelican Therapeutics, Inc.                                
Percentage of non-controlling interest acquired                     15.00% 15.00% 15.00% 15.00%    
Grant and contract revenue | Maximum                                
Amount awarded from NIH grant $ 200,000                              
Lab equipment                                
Reimbursement Included in operating lease right of use asset                             $ 10,200,000  
Reimbursement of expenses, capitalized                             $ 13,200,000  
Common stock warrants                                
Warrants exchanged | shares                     0 0        
Revision of Prior Period                                
Income tax expense (benefit)             $ 300,000     $ 300,000            
Heat I                                
Ownership interest in subsidiary     100.00%                          
Pelican Therapeutics, Inc.                                
Ownership interest in subsidiary     85.00%               85.00% 85.00% 85.00% 85.00%   80.00%
Heat I, Inc. and Pelican                                
Shares issued in acquisition | shares     35,000                          
Pelican Therapeutics, Inc.                                
Contingent consideration liability, written off                     $ 3,300,000          
Pelican Therapeutics, Inc. | Grant and contract revenue                                
Revenue                     15,200,000   $ 15,200,000 $ 15,200,000    
Remaining grant amount receivable                     $ 1,500,000   $ 1,500,000 $ 1,500,000    
Pelican Therapeutics, Inc. | Grant and contract revenue | Tranche 1                                
Revenue         $ 1,800,000                      
Pelican Therapeutics, Inc. | Grant and contract revenue | Tranche 2                                
Revenue       $ 6,500,000                        
Pelican Therapeutics, Inc. | Grant and contract revenue | Tranche 3                                
Revenue   $ 5,400,000                            
Pelican Therapeutics, Inc. | Grant and contract revenue | Maximum                                
Amount awarded from CPRIT grant           $ 15,200,000