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Goodwill and other intangible assets (Details) - USD ($)
3 Months Ended 12 Months Ended
Apr. 18, 2022
Sep. 30, 2022
Dec. 31, 2021
Dec. 31, 2022
Dec. 31, 2017
Mar. 31, 2023
Goodwill and other intangible assets            
Balance of finite-lived intangible assets       $ 8,669,375   $ 8,305,625
Pelican Therapeutics, Inc.            
Goodwill and other intangible assets            
Goodwill acquired         $ 2,200,000  
In-process research and development impairment   $ 3,500,000        
Goodwill impairment loss     $ 1,500,000      
Pelican Therapeutics, Inc. | In-process R&D.            
Goodwill and other intangible assets            
Finite-lived intangible assets acquired         $ 5,900,000  
Carrying value written down     5,900,000      
Intangible assets fair value     3,500,000      
In-process research and development impairment     $ 2,400,000      
Elusys Therapeutics            
Goodwill and other intangible assets            
Goodwill acquired $ 3,300,000          
Finite-lived intangible assets acquired $ 9,700,000          
In-process research and development impairment       $ 0    
Remaining amortization period 80 months